Paeoniflorin is a glycoside isolated from the root of Paeonia lactiflora. Paeoniflorin has been used as an anticonvulsant and has hypoglycemic effect.
PA-824 is a novel, orally active nitroimidazole derivative with antimycobacterial activity for use in tuberculosis-related studies.
TAK-779 is a potent and selective nonpeptide antagonist of CCR5, with a Ki of 1.1 nM for CCR5.
Elesclomol (STA-4783) is a novel oxidative stress inducer that acts on tumor cells and promotes their apoptosis, and is a strong copper ion-carrier that can be used for cuproptosis studies.
WZ4002 is a novel, selective EGFR kinase inhibitor against EGFR T790M (mutation of the gatekeeper T790 residue) with IC50 of 8 nM.
CYN 154806, a cyclic octapeptide, is a potent and selective somatostatin sst2 receptor antagonist.
Kemptide is a synthetic heptapeptide that acts as a specific substrate for camp-dependent protein kinase (PKA).
Rilonacept (Arcalyst), a dimeric fusion protein, is a interleukin 1 inhibitor. Rilonacept consists of the ligand-binding domains of the extracellular portions of the IL-1R components linked to the Fc portion of human IgG1. Rilonacept can be used for the research of cryopyrin-associated periodic syndromes.
[Leu5]-Enkephalin is a five amino acid endogenous peptide that acts as an agonist of opioid receptors.
Neoprzewaquinone A is isolated from the roots of Salvia miltiorrhiza, it is an active ingredient of S. miltiorrhiza, inhibits breast cancer cell migration and promotes smooth muscle relaxation by targeting PIM1 and blocking the ROCK2/STAT3 pathway.