3-Chloro-L-tyrosine is a specific marker of myeloperoxidase-catalyzed oxidation, and it is markedly elevated in low density lipoprotein isolated from human atherosclerotic intima.
Fipexide, a parachloro-phenossiacetic acid derivative. Fipexide (FPX) is a novel chemical inducer that promotes callus formation and shoot regeneration in plants. Fipexide reduces striatal adenylate cyclase activity. Fipexide has positive effect on cognitive performance by dopaminergic neurotransmission. Fipexide is used for senile dementia research.
4-(Phenyldiazenyl)benzoic acid is a photosensitive and photoswitchable TRPA1 agonist that can be used for the research of pain signaling.
BCL6-IN-6 is a potent inhibitor of transcriptional suppressor B-cell lymphoma 6 (BCL6). Bcl6-in-6 has the potential to study diffuse large B-cell lymphoma (DLBCL).
CEP-40783 (RXDX-106) is a potent, selective and orally available inhibitor of AXL and c-Met with IC50 values of 7 nM and 12 nM, respectively.
UK-78282 is a novel, potent and selective Kv1.3 blocker with an IC50 of 200 nM. UK-78282 effectively suppresses human T-lymphocyte activation in vitro. UK-78282 binds to residues at the inner surface of the channel overlapping the site of action of verapamil.
HCV-796 is a specific inhibitor of HCV NS5B polymerase with IC50 of 0.01-0.14 μM for genotype 1, with EC50 of 5 nM and 9 nM against genotype 1a and 1b replicons.
Oxybutynin Hydrochloride is an anticholinergic compound used to relieve urinary and bladder load.
GSK690693 is a potent Akt inhibitor (Akt1 IC50 = 2 nM, Akt2 IC50 = 13 nM, Akt3 IC50 = 9 nM) which also inhibited the phosphorylation of the downstream target GSK3b in cells.