1-Octacosanol is a linear aliphatic 28-carbon fatty alcohol with anti-fatigue properties.
Cisplatin is an inorganic platinum complex that inhibits DNA synthesis by forming DNA crosslinking agents, inactivates GPXs, reduces cell GSH and induces iron death in HCT116 and A549 cells.
Prexasertib (LY2606368) is a substrate ATP competitively selective inhibitor of CHK1 and CHK2 with IC50 values of
Sennoside D is an anthraquinone glycoside found in the leaves and pods of senna (Cassia Angustifolia).
GSK2837808A is a potent, selective lactate dehydrogenase A (LDHA) inhibitor with IC50s of 2.6 and 43 nM for hLDHA and hLDHB, respectively.
Cucurbitadienol has significant anti-inflammatory, anti-tumor effect, is also CucurbitacinBE compounds biosynthesis the key intermediate. Cucurbitadienol synthase, the first committed enzyme for cucurbitacin biosynthesis, is a distinct enzyme from cycloartenol synthase for phytosterol biosynthesis. CYP87D18 catalyzed the oxidation of cucurbitadienol at...
Sutimlimab is the first inhibitor of complement protein component 1,s subcomponent (C1s) for the study of cold agglutinin syndrome, a serine protease that cleaves C4 and C2 to form C3 convertase.
ACP-105 is an orally available, selective amd potent androgen receptor modulator (SARM), with pEC50s of 9.0 and 9.3 for AR wild type and T877A mutant, respectively.
Pyrantel pamoate is a deworming agent in the treatment of hookworms (all species) and roundworms in domesticated animal; acts as a depolarizing neuromuscular blocking agent.
Daidzin is an isoflavone that has anti-oxidant, anti-carcinogenic, and anti-atherosclerotic activities; directly inhibits mitochondrial aldehyde dehydrogenase 2 (IC50 = 80 nM) and is an effective anti-dipsotropic isoflavone.
Clovamide is a natural phenolic compound with anti-inflammatory and neuroprotective effects, a potent antioxidant, and an excellent ROS and oxygen free radical scavenger.
Rabeprazole Related Compound E is the active metabolite of Rabeprazole and an orally active proton pump inhibitor that inhibits gastric acid secretion by interacting with (H+/K+)-ATPase in gastric lining cells. In addition, Rabeprazole Related Compound E significantly inhibits the activity of Helicobacter pylori and can be used in studies related to...