Pitolisant hydrochloride is a potent and selective nonimidazole inverse agonist at the recombinant human histamine H3 receptor (Ki=0.16 nM).
Cinaciguat is an activator of guanylate cyclase (sGC), and used for acute decompensated heart failure.
SB-242235 is a potent and selective p38 MAP kinase inhibitor, with an IC50 of 1.0 μM in primary human chondrocytes.
SB-242235 is a potent and selective p38 MAP kinase inhibitor, with an IC50 of 1.0 μM in primary human chondrocytes.
Adenosine monophosphate is a key cellular metabolite regulating energy homeostasis and signal transduction.
Guanosine 5'-triphosphate trisodium salt (5'-GTP trisodium salt) is an activator of the signal transducing G proteins which are involved in various cellular processes including proliferation, differentiation, and activation of several intracellular kinase cascades.
LP-533401 is a Tryptophan hydroxylase 1 inhibitor that regulates serotonin production in the gut.
Bivalirudin TFA is a synthetic 20 residue peptide which reversibly inhibits thrombin.
LP-533401 is a Tryptophan hydroxylase 1 inhibitor that regulates serotonin production in the gut.
LP-533401 is a Tryptophan hydroxylase 1 inhibitor that regulates serotonin production in the gut.
Auxinole is a potent auxin antagonist of TIR1/AFB receptors, binding TIR1 to block the formation of the TIR1-IAA-Aux/IAA complex and so inhibits auxin-responsive gene expression.