Quinine is a potassium channel inhibitor that inhibits WT mouse Slo3 (KCa5.1) channel currents evoked by voltage pulses to +100 mV with an IC50 of 169 μM.
The MitoSOX Red Mitochondrial Superoxide Indicator (MitoSOX) is a novel fluorescent probe specifically targeted to live cell lines. It has membrane permeability and produces strong Red fluorescence when combined with nucleic acid. Its maximum excitation/emission wavelength is 510/580nm.
Acetic acid is one of the most important fatty acids. In nature, it generally exists in free form or ester form in many plants.
IWP-O1 is a porcn inhibitor with an EC50 value of 80 pM in a cultured cell reporter assay of Wnt signaling and effectively suppresses the phosphorylation of Dvl2/3 in HeLa cells.
IWP-O1 is a porcn inhibitor with an EC50 value of 80 pM in a cultured cell reporter assay of Wnt signaling and effectively suppresses the phosphorylation of Dvl2/3 in HeLa cells.
Simufilam (PTI-125) Dihydrochloride is a small molecule modulator that preferentially binds altered FLNA and restores its native conformation, restoring receptor and synaptic activities and reducing its α7nAChR/TLR4 associations and downstream pathologies.
Simufilam (PTI-125) Dihydrochloride is a small molecule modulator that preferentially binds altered FLNA and restores its native conformation, restoring receptor and synaptic activities and reducing its α7nAChR/TLR4 associations and downstream pathologies.
Asundexian (BAY2433334) is a reversible inhibitor of the active site of Factor XIa. Asundexian inhibits the activity of FXIa by directly, efficiently, and reversibly binding to its active site. the IC50 of human FXIa in Asundexian inhibition buffer is 1 nM.
Asundexian (BAY2433334) is a reversible inhibitor of the active site of Factor XIa. Asundexian inhibits the activity of FXIa by directly, efficiently, and reversibly binding to its active site. the IC50 of human FXIa in Asundexian inhibition buffer is 1 nM.
4-Deoxypyridoxine hydrochloride is a vitamin B6 antimetabolite with diverse biological activities.
4-Deoxypyridoxine hydrochloride is a vitamin B6 antimetabolite with diverse biological activities.
L-dihydroorotic acid (L-dihydroorotate) is an intermediate product of pyrimidine metabolism that can be reversibly hydrolyzed by dihydroorotase to yield acyclic L-ureidosuccinic acid.