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Chemical Hay 28543 productos.
Treosulfan
Treosulfan (NSC 39069) is a bifunctional alkylating agent with activity in ovarian cancer and other solid tumor types.
Purpureaside C
Purpureaside C is a phenolic glycoside which has significant proinflammatory activity.
Prinomastat
Prinomastat (AG3340) is a broad spectrum, potent, orally active metalloproteinase (MMP) inhibitor with IC50s of 79, 6.3 and 5.0 nM for MMP-1, MMP-3 and MMP-9, respectively.
Indole
Indole (2,3-Benzopyrrole) is an aromatic heterocyclic organic compound that is widely distributed in the natural environment and can be produced by a variety of bacteria.
Ethylvanillin
Ethylvanillin is the organic flavorant. It is about three times as potent as vanillin and used in the production of chocolate.
Kobusin
Kobusin, a dioxygenated lignan isolated from Pnonobio biondii Pamp, is also an activator of the CFTR and CaCCgie chloride channels and an inhibitor of the ANO1/CaCC (calcium-activated chloride channel) channel.
Enasidenib
Enasidenib is an oral, potent, reversible, selective inhibitor of the IDH2 mutant enzymes, with IC50s of 100 and 400 nM against IDH2R140Q and IDH2R172K, respectively.
PF-04965842
Abrocitinib is an orally active and selective JAK1 inhibitor with an IC50 value of 29 nM. Abrocitinib reversibly inhibits JAK1 kinase by blocking its ATP-binding site. Abrocitinib (PF-04965842) inhibited TYK2 activity (IC50, 1.253 μM) and phosphorylation of STAT1, STAT3, and STAT5 after stimulation. It can be used in the study of autoimmune diseases.
Timolol Maleate
Timolol Maleate is a non-selective, beta-adrenergic receptor antagonist for β1/β2 with Ki of 1.97 nM/2.0 nM.
MLN2480
MLN2480 is an orally active, CNS-permeable, highly selective inhibitor of type II RAF kinase that inhibits both monomeric (class I mutant) and dimeric forms of RAF and does not cause aberrant activation of the MAPK pathway caused by type I RAF inhibitors. In addition, MLN2480 inhibits the growth of tumors harboring BRAF fusions or BRAF V600 mutations and...
EZM0414
EZM0414 is a potent, selective, oral bioavailable SETD2 inhibitor (IN SETD2 biochemical analysis, IC50=18 nM; In cell analysis, IC50=34 nM). EZM0414 can be used to study relapsed or refractory multiple myeloma and diffuse large B-cell lymphoma.
AMN 082 dihydrochloride
AMN 082 dihydrochloride is a the first selective mGlu 7 agonist.