Chemical
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- Catálogos PDF
Chemical Hay 28543 productos.
GSK2269557
Nemiralisib, also known as GSK-2269557, is a potent and selective PI3Kδ inhibitor(pKi = 9.9).
4',5,7-Trimethoxyflavone
5,7,4'-Trimethoxyflavone is a natural product isolated from the Thai plant Kaempferia parviflora (KP) and a CFTR activator with an EC50 of 64 μM. In addition, 5,7,4'-Trimethoxyflavone induces apoptosis, increases the activation of caspase-3 protein hydrolysis, and the degradation of poly (ADP-ribose) polymerase (PARP) protein.
Reparixin
Reparixin is a noncompetitive allosteric inhibitor of IL-8 (CXCL8) activation of CXCR1 and CXCR2 chemokine receptors with IC50 of 1 and 100 nM, respectively.
Ro 25-6981 maleate salt
Ro 25-6981 maleate salt is a potent and selective antagonist of NMDA glutamate receptors containing the NR2B subunit with IC50 values of .009 μM for NR2B vs. 52 μM for NR2A subunits. Ro 25-6981 has been shown to have neuroprotectant effects and to reduce inflammatory and neuropathic pain in rodent models.
Calindol hydrochloride
Calindol is a calcimimetic Ca Sensing Receptor (CaSR) agonist.
ASP7663
ASP7663 is an orally active and selective TRPA1 agonist.
TRV130 hydrochloride
TRV130 (Oliceridine) hydrochloride is a novel μ-opioid receptor (MOR) G protein-biased ligand.
OSMI-1
OSMI-1 is a cell permeable inhibitor of OGT (O-GlcNAc transferase) with an IC50 value of 2.7 μM.
Riociguat (BAY 63-2521)
Riociguat (BAY 63-2521) is an oral soluble guanylate cyclase (GC) stimulator, used in the research of ipulmonary hypertension.
BILN 2061
BILN 2061 is a specific and potent peptidomimetic inhibitor of the HCV NS3 protease with IC50 of 3.0 nM.
Lubiprostone
Lubiprostone is a gastrointestinal agent used for the treatment of idiopathic chronic constipation.
Dydrogesterone
Dydrogesterone is an orally active progestogen which acts directly on the uterus, producing a complete secretory endometrium in an estrogen-primed uterus.