Sodium Iodide (sodium iodide) is a metal iodide salt that can be used to construct mouse models of thyroiditis, as well as rat models of autoimmune thyroiditis.
6-Aminocaproic acid (EACA) is a derivative and analogue of the amino acid lysine, it is also a potent and orally active inhibitor of plasmin and plasminogen.
Palbociclib (PD0332991) Isethionate is a highly selective inhibitor of CDK4/6 with IC50 of 11 nM/16 nM. It shows no activity against CDK1/2/5, EGFR, FGFR, PDGFR, InsR, etc. Phase 2/3.
Gracillin is a glycoside, more particularly to a Spirostanol saponin, which can be found among others in many plants of the genus Dioscorea, Paris and Costacea, for example in tamus communis.
Epimedoside A is A flavonoid isolated from the roots of Epimedium Wushanense. Epimedoside A has significant antioxidant activity in vitro.
ABT-348 is a novel ATP-competitive inhibitor of Aurora B, Aurora C and Aurora A with IC50 of 7 nM, 1 nM and 120 nM, respectively.
Trazodone HCl is an antidepressant belonging to the class of serotonin receptor antagonists and reuptake inhibitors for treatment of anxiety disorders.
Fluvastatin sodium is an orally active, potent and competitive HMG-CoA reductase inhibitor with IC50 value between 40 and 100 nM at human liver microsomes. Fluvastatin sodium protects vascular smooth muscle cells against oxidative stress through the Nrf2-dependent antioxidant pathway.
JKE-1674 is an inhibitor of glutathione peroxidase 4 (GPX4) and an active metabolite of the GPX4 inhibitor ML-210. JKE-1674 reduces viability of LOX-IMVI cancer cells and in a panel of additional cancer cell lines, an effect that can be blocked by the ferroptosis inhibitor ferrostatin-1.