Ziyuglycoside II from Sanguisorba officinalis L. Triterpenoid saponins extracted from the. Ziyuglycoside II induces reactive oxygen species (ROS) production and apoptosis. It has anti-inflammatory and anticancer effects.
Pentagastrin (ICI-50123) is a synthetic polypeptide that has effects like gastrin when given parenterally.
ACY-957 is an orally active and selective inhibitor of HDAC1 and HDAC2, with IC50s of 7 nM, 18 nM, and 1300 nM against HDAC1/2/3, respectively, and shows no inhibition on HDAC4/5/6/7/8/9.
CM-272 is a first-in-class, reversible dual small molecule inhibitor of G9a and DNMTs in hematologic malignancies.
N-Glycolylneuraminic acid is a nonhuman sialic acid molecule synthesized in pigs but not in humans. N-Glycolylneuraminic acid works as a decoy receptor of N-Glycolylneuraminic acid-binding influenza A viruses (IAVs).
Sodium Hyaluronic is is an anionic, nonsulfated glycosaminoglycan distributed widely throughout connective, epithelial, and neural tissues, it is used as a humectant to increase moisture in the skin, it may also serve as an emulsifier.
2, 4-diamino-6-hydroxypyrimidine is a specific inhibitor of GTP cyclohydrolase I, a rate-limiting enzyme involved in de novo protein synthesis. 2, 4-diamino-6-hydroxypyrimidine can block the synthesis of Tetrahydrobiopterin (BH4) and inhibit the production of NO.
CC-401 hydrochloride is a potent inhibitor of all three forms of JNK with Ki of 25 to 50 nM.
Elagolix is a highly potent, selective, orally-active, short-duration, non-peptide antagonist of the gonadotropin-releasing hormone receptor (GnRHR) (KD = 54 pM). Target: GnRH in vitro: Elagolix is a short-acting, nonpeptide, GnRH antagonist, administered orally, that unlike injectable depot GnRH agonists and antagonists, produces a dose-dependent...
BP-1-102 is a potent, orally bioavailable and selective STAT3 inhibitor with IC50 of 6.8 μM.
Mevalonic acid lithium salt, a precursor in the mevalonate pathway, is essential for cell growth and proliferation.
SR-717 is a non-nucleotide STING agonist with EC50s of 2.1 μM and 2.2 μM in ISG-THP1 (WT) and ISG-THP1 cGAS KO (cGAS KO) cell lines, respectively.