Abacavir is a commonly used nucleoside analogue with potent antiviral activity against HIV-1.
Tranylcypromine HCl is a monoamine oxidase inhibitor, which inhibits CYP2A6 with Ki of 0.08 μM and 0.2 μM in cDNA-expressing microsomes and Human Liver Microsomes, respectively. Tranylcypromine hydrochloride inhibits LSD1, MAO A and MAO B with IC50s of 20.7, 2.3 and 0.95 μM, respectively.
Lofexidine hydrochloride is an selective α2A-adrenergic receptor agonist.
CYT997 is a potent microtubule polymerization inhibitor with IC50 of 10-100 nM in cancer cell lines.
Loratadine is a histamine H1 receptor antagonist, used to treat allergies. Also acts as a selective inhibitor of B(0)AT2 with IC50 of 4 μM.
Ganoderic-acid-A inhibits of the JAK-STAT3 signaling pathway, also inhibit proliferation, viability, ROS.
Anethole is a kind of aromatic compounds used as flavoring, is a derivative of Phenylpropene, widely exists in nature.
Basroparib is an orally active selective inhibitor of end-anchor polymerase (TNKS) and an inhibitor of ribose polymerase (PARP) with antitumor activity.