Chemical
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- Catálogos PDF
Chemical Hay 28543 productos.
Bimiralisib
Bimiralisib (PQR309) is a potent, brain-penetrant, orally bioavailable inhibitor of PI3K and mTOR, with potential antineoplastic activity.
AVJ16
AVJ16 is a cancer cell migration inhibitor that targets the insulin-like growth factor 2 mRNA binding protein IGF2BP1 to inhibit the migration of H1299 cells with high endogenous IGF2BP1 expression.
Finerenone
Finerenone (BAY 94-8862) is a third generation selective, oral active, non-steroidal halocorticoid receptor (MR) antagonist (IC50=18 nM). Finerenone showed good selectivity (>500-fold) compared to glucocorticoid receptor (GR), androgen receptor (AR), and progesterone receptor (AR). Finerenone has potential applications in the study of heart and kidney...
Obeticholic Acid (INT-747)
Obeticholic Acid (INT-747) is a potent, orally active, selective farnesoid X receptor (FXR) agonist with an EC50 of 99 nM.May be used in studies related to non-alcoholic steatohepatitis (NASH).
GSK256066
GSK256066 is a selective phosphodiesterase 4 (PDE4)inhibitor with an IC50 of 3.2 pM. *The compound is unstable in solutions, freshly prepared is recommended
CY5
Cy5 (Sulfo-Cyanine5) is a reactive dye for the labeling of amino-groups in peptides, proteins, and oligonucleotides. CY dyes are of en used for the labeling of proteins, antibodies and small molecular compounds. For the labeling of protein antibodies, the combination can be completed through a simple mixing reaction.
BLT-1
Block lipid transport-1 (BLT-1) is a specific inhibitor of the SR-BI (Scavenger receptor, class B, type I) mediated lipid transfer.
L-Alanyl-L-glutamine
L-Alanyl-L-glutamine (L-Ala-Gln) is a stable form of L-glutamine; commonly used in cell culture.
CX-6258
CX-6258 is a potent, orally efficacious Pim 1/2/3 kinase(IC50=5 nM/25 nM/16 nM) inhibitor with excellent biochemical potency and kinase selectivity.
K41498 TFA
K41498 TFA is an antisauvagine-30 (aSvg-30) analog and a strongly selective CRF2 receptor antagonist with Ki values of 0.66 nM, 0.62 nM, and 425 nM for human CRF2α, CRF2β, and CRF1 receptors, respectively.K41498 TFA inhibits sauvagine-stimulated cAMP accumulation in hCRF2α/hCRF2β expressing cells. K41498 TFA can be used in hypotension studies.
Bergenin
Bergenin is a cell protection and antioxidant polyphenol found in many medicinal plants. Bergenin has a wide range of hepatoprotective, anti-inflammatory, immunomodulatory, anti-tumor, antiviral, and antifungal effects.
BAY 61-3606 dihydrochloride
BAY-61-3606 is a potent and selective inhibitor of Syk kinase (Ki = 7.5 nM).