Chemical
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- Catálogos PDF
Chemical Hay 28543 productos.
MRT-83
MRT-83 is a potent antagonist of Smo, with an IC50 in the nanomolar range. MRT-83 also blocks Hedgehog (Hh) signaling.
Perillyl Alcohol
Perillyl Alcohol is a monoterpene, it is active in inducing apoptosis in tumor cells without affecting normal cells.
Zoliflodacin
Zoliflodacin (ETX0914;AZD0914) is a novel spiropyrimidinetrione bacterial DNA gyrase/topoisomerase inhibitor. Zoliflodacin has potent in vitro antibacterial activity against Gram-positive and Gram-negative organisms, including S. aureus with the MIC90 of 0.25 μg/mL.
Glyoxylic acid
Glyoxylic acid is an organic compound that can be used to construct animal models of kidney stones.
Progoitrin
Progoitrin (2-hydroxy-3-butenyl glucosinolate, PRO) is a naturally occurring thioglucoside with anti-thyroidal activity.
Norbergenin
Norbergenin, the O-demethyl derivative of bergenin, shows moderate antioxidant activity (IC50 13 μM in DPPH radical scavenging; 32 μM in superoxide anion scavenging).
2-PMPA tetrasodium
2-PMPA (PMPA tetrasodium salt) is a potent and selective inhibitor of glutamate carboxypeptidase II (GCPII) with an IC50 of 300 pM.
BH3I-1
BH3I-1 is a Bcl-XL-BH3 domain interaction inhibitor with Ki of 2.4 μM (by fluorescence polarization).It is a selective inhibitor of Bcl-2 family proteins.
Edicotinib
Edicotinib (JNJ-40346527) is a potent, selective, blood-brain permeable and orally active CSF-1R inhibitor.IC50 3.2 nM. Edicotinib has less inhibitory effect on KIT and FLT3,IC50 The values are 20 nM and 190 nM, respectively. Edicotinib inhibits the expansion of microglia, weakens the proliferation of microglia and neurodegenerative degeneration....
5,5-Dimethyloxazolidine-2,4-dione
Dimethadione is an anticonvulsant that is the active metabolite of trimethadione.
Pemetrexed Disodium Hydrate
Pemetrexed Disodium Hydrate is a novel antifolate and antimetabolite for TS, DHFR and GARFT with Ki of 1.3 nM, 7.2 nM and 65 nM, respectively.
ST2825
ST-2825 is MyD88 inhibitor.