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Edicotinib
AM-M10937-50mg
Producto nuevo
Edicotinib (JNJ-40346527) is a potent, selective, blood-brain permeable and orally active CSF-1R inhibitor.IC50 3.2 nM. Edicotinib has less inhibitory effect on KIT and FLT3,IC50 The values are 20 nM and 190 nM, respectively. Edicotinib inhibits the expansion of microglia, weakens the proliferation of microglia and neurodegenerative degeneration. Edicotinib can be used in the study of Alzheimer's disease and rheumatoid arthritis.
Al comprar este producto puede obtener hasta 68 puntos de fidelidad. Su cesta totalizará 68 puntos de fidelidad que se puede(n) transformar en un cupón de descuento de 13.60EUR.
Ficha de datos
| Size | 50mg |
| Molecular Weight | C27H35N5O2 |
| Research Area | CSF-1R (c-Fms) |
| CAS Number | '1142363-52-7 |
| Smiles | CC1(C)CCC(=CC1)C2=NC(=CC=C2NC(=O)C3=NC=C([NH]3)C#N)C4CC(C)(C)OC(C)(C)C4 |