NBQX (FG9202) is a potent and selective AMPA receptor antagonist. NBQX has neuroprotective and anticonvulsant activity. It is more selective than CNQX.
Argireline (Acetyl hexapeptide-3) is a non-toxic, skin-permeable, antiwrinkle peptide. Argireline significantly inhibits Ca2+ dependent neurotransmitter release (acetylcholine) at the neuromuscular junction.
Riociguat (BAY 63-2521) is an oral soluble guanylate cyclase (GC) stimulator, used in the research of ipulmonary hypertension.
AT-13148 is an oral, ATP-competitive inhibitor of multi-AGC kinases with potent pharmacodynamic and antitumor activity, which shows a distinct mechanism of action from other AKT inhibitors.
Ozagrel is a potent and selective thromboxane A2 synthetase inhibitor with an IC50 of 4 nM.
Notoginsenoside Fa is a protopanaxadiol (ppd)-type saponin isolated from P. notoginseng, could possibly activate and recover the function of degenerated brain.
Picfeltarraenin X is an AChE inhibitor, which is a triterpenoid isolated from Picria fel-terrae Lour.
GPR39-C3 is a potent and orally available GPR39 agonist with EC50 values of 0.4 and 0.8 nM for rat and human receptors respectively.
Punicalin is a hydrolyzed tannin that can be obtained from Punica granatum L. Or from the leaves of Terminalia catappa L. Punicalin is an anti-hepatitis B virus (HBV) drug with anti-inflammatory activity.
Salubrinal is a selective inhibitor of eIF2α dephosphorylation and inhibits ER stress-mediated apoptosis with EC50 of ~15 μM.
DOPE (1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine) forms heterogenous liposomes with N-[1-(2,3-dioleoyloxy)propyl]-N,N,N-trimethylammonium methylsulfate (DOTAP), which are used as delivery vehicles for therapeutic agents.