Vancomycin is a glycopeptide antibiotic as well as a macrocyclic compound that can be used to construct models of bronchiectasis combined with lung infections, as well as for studies related to various bacterial infectious conditions.
TT-10 (TAZ-K) is an activator of YES-associated protein (YAP)-transcriptional enhancer factor domain (TEAD) activity. TT-10 can be used for the research of heart diseases accompanied by cardiomyocyte loss.
Salinosporamide A (NPI-0052, Marizomib) is a novel marine derived proteasome inhibitor which inhibits CT-L, C-L, and T-L proteasome activities in human erythrocyte-derived 20S proteasomes with EC50 of 3.5 nM, 430 nM, 28 nM.
Asatone is an active component isolated from Radix et Rhizoma Asari, with anti-inflammatory effect via activation of NF-κB and donwn regulation of p-MAPK (ERK, JNK and p38) pathways.
Elamipretide TFA, also known as MTP-131, is a cardiolipin peroxidase inhibitor and mitochondria-targeted peptide.
LDC1267 is a highly selective inhibitor of TAM (Tyro3,Axl and Mer) kinases with IC50 values of
Elesclomol (STA-4783) is a novel oxidative stress inducer that acts on tumor cells and promotes their apoptosis, and is a strong copper ion-carrier that can be used for cuproptosis studies.
Disitertide (P144) diammonium is a polypeptide inhibitor of transforming growth factor TGFβ1, specifically blocking its interaction with the receptor. Disitertide diammonium was also an inhibitor of PI3K and an inducer of apoptosis.
YHO-13177 is a potent and specific inhibitor of breast cancer resistance protein (BCRP/ABCG2).