A-205804 is a potent and selective inhibitor of E-selectin and ICAM-1 expression with IC50 of 20 nM and 25 nM respectively.
A-205804 is a potent and selective inhibitor of E-selectin and ICAM-1 expression with IC50 of 20 nM and 25 nM respectively.
A-286982 is a potent inhibitor of the LFA-1/ICAM-1 interaction. A-286982 binds to the I domain allosteric site (IDAS).
A-286982 is a potent inhibitor of the LFA-1/ICAM-1 interaction. A-286982 binds to the I domain allosteric site (IDAS).
A-286982 is a potent inhibitor of the LFA-1/ICAM-1 interaction. A-286982 binds to the I domain allosteric site (IDAS).
A-286982 is a potent inhibitor of the LFA-1/ICAM-1 interaction. A-286982 binds to the I domain allosteric site (IDAS).
A-317491 is a potent, selective and non-nucleotide antagonist of P2X3 and P2X2/3 receptors, with Kis of 22, 22, 9, and 92 nM for hP2X3, rP2X3, hP2X2/3, and rP2X2/3, respectively. A-317491 is highly selective for other P2 receptors and neurotransmitter receptors, ion channels, and enzymes (IC50>10 μM).
A-317491 is a potent, selective and non-nucleotide antagonist of P2X3 and P2X2/3 receptors, with Kis of 22, 22, 9, and 92 nM for hP2X3, rP2X3, hP2X2/3, and rP2X2/3, respectively. A-317491 is highly selective for other P2 receptors and neurotransmitter receptors, ion channels, and enzymes (IC50>10 μM).
A-317491 is a potent, selective and non-nucleotide antagonist of P2X3 and P2X2/3 receptors, with Kis of 22, 22, 9, and 92 nM for hP2X3, rP2X3, hP2X2/3, and rP2X2/3, respectively. A-317491 is highly selective for other P2 receptors and neurotransmitter receptors, ion channels, and enzymes (IC50>10 μM).
A-317491 is a potent, selective and non-nucleotide antagonist of P2X3 and P2X2/3 receptors, with Kis of 22, 22, 9, and 92 nM for hP2X3, rP2X3, hP2X2/3, and rP2X2/3, respectively. A-317491 is highly selective for other P2 receptors and neurotransmitter receptors, ion channels, and enzymes (IC50>10 μM).
A-317491 sodium salt hydrate is a potent, selective and non-nucleotide antagonist of P2X3 and P2X2/3 receptors, with Kis of 22, 22, 9, and 92 nM for hP2X3, rP2X3, hP2X2/3, and rP2X2/3, respectively.
A-317491 sodium salt hydrate is a potent, selective and non-nucleotide antagonist of P2X3 and P2X2/3 receptors, with Kis of 22, 22, 9, and 92 nM for hP2X3, rP2X3, hP2X2/3, and rP2X2/3, respectively.