Chemical
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- Catálogos PDF
Chemical Hay 28543 productos.
S1PR1 modulator 1
S1PR1 modulator 1 is a selective S1PR1 inhibitor, with a pIC50 of 7.6, with >40- and >80-fold selectivity, over the other S1PR isoforms S1PR2/3/4.
GW280264X
GW280264X is an ADAM17 inhibitor.
Cordycepin
Cordycepin (3'-Deoxyadenosine) is a nucleoside derivative isolated from Cordyceps, inhibits IL-1β-induced MMP-1 and MMP-3 expression in rheumatoid arthritis synovial fibroblasts.
Dehydrocorydaline
Dehydrocorydaline is an alkaloid, it can regulate protein expression of Bax, Bcl-2. Dehydrocorydaline elevates p38 MAPK activation.
TC LPA5 4
TC LPA5 4 is a specific non-lipid LPA5 (GPR92) antagonist (IC50=0.8 μM in LPA5-RH7777 cells). Shows selectivity for LPA5 against 80 other screening targets.TC LPA5 4 was shown to inhibit LPA-induced aggregation of isolated human platelets.TC LPA5 4 inhibits proliferation and migration of thyroid cancer cells.
Teduglutide
Teduglutide is a glucagon-like peptide-2 (GLP-2) analogue used for the treatment of short-bowel syndrome.
SR-95531
SR-95531 is a specific GABAA receptor antagonist that does not affect GABA-transaminase or glutamate-decarboxylase activities.
Sodium-Demethylcantharidate
Sodium Demethylcantharidate is an endogenous metabolite. Sodium Demethylcantharidate induces apoptosis in hepatocellular carcinoma cells via ER stress, it shows excellent anticancer activity against multiple types of cancer.
Ro 48-8071
Ro 48-8071 is an inhibitor of OSC(Oxidosqualene cyclase; IC50=6.5 nM) that has low-density lipoprotein (LDL) cholesterol lowering activity.
Calycosin-7-glucoside
Calycosin-7-o -β-D-glucoside is an isoflavone isolated from Astragalus membranaceus. Calycosin-7-o -β -D-Glucoside has a variety of biological activities, such as neuroprotective, cardioprotective, anti-inflammatory and antioxidant effects.
BG45
BG45 is a potent and selective HDAC3 inhibitor with selectivity for HDAC3 (IC50 = 289 nM) over HDAC1, 2, 6.
Tideglusib
Tideglusib (NP031112, NP-12) is a potent non ATP-competitive inhibitor of GSK3 with IC50 of 60 nM.