Chemical
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Chemical Hay 28543 productos.
aurantiamide-acetate
Aurantiamide acetate is a selective and orally active cathepsin inhibitor isolated from Portulaca Oleracea L. Aurantiamide acetate has anti-inflammatory activity and can be used to study inflammatory diseases.
EDC.HCl Crosslinker
EDC.HCl Crosslinker is a zero-length crosslinker that can be used to conjugate carboxyl functional groups to primary amines.
Methylthiouracil
Methylthiouracil is an anti-thyroid agent. Methylthiouracil inhibits TNF-α and IL-6 production and NF-κB and ERK1/2 activation.
CHIR 99021 trihydrochloride
Laduviglusib (CHIR-99021) trihydrochloride is a potent and selective GSK-3α/β inhibitor with IC50s of 10 nM and 6.7 nM. Laduviglusib trihydrochloride shows >500-fold selectivity for GSK-3 over CDC2, ERK2 and other protein kinases. Laduviglusib trihydrochloride is also a potent Wnt/β-catenin signaling pathway activator.
Tuberostemonine
Tuberostemonine is an alkaloid, an antimalarial that targets plasmodium falciparum ferridogen-NADP + reductase (pfFNR).
Rosuvastatin Sodium
Rosuvastatin Sodium is a competitive HMG-CoA reductase (HMGCR) inhibitor, with an IC50 of 11 nM. Rosuvastatin Sodium potently blocks hERG current with an IC50 of 195 nM. Rosuvastatin Sodium reduces the expression of the mature hERG and the interaction of heat shock protein 70 (Hsp70) with the hERG protein. Rosuvastatin Sodium effectively lowers...
PXS-5153A
PXS-5153A is a potent, selective, orally active and fast-acting lysyl oxidase like 2/3 enzymatic (LOXL2/LOXL3) inhibitor, with an IC50 of
MRTX1133
MRTX1133 is a first-in-class, potent and highly selective KRAS G12D inhibitor. MRTX1133 targets the KRAS G12D protein in both active and inactive states. MRTX1133 selectively inhibits KRAS G12D mutant, but not KRAS wild-type, tumor cells.
Pregabalin
Pregabalin (Lyrica) is a 3-isobutyl derivative of gamma-amino butyric acid (GABA) with anti-convulsant, anti-epileptic, anxiolytic, and analgesic activities.
Decoglurant
Decoglurant (also known as RO4995819) is a negative allosteric modulator of the mGlu2 and mGlu3 receptors.
BMS303141
BMS303141 is a potent ATP-citrate lyase (ACL) inhibitor with IC50 value of 0.13 uM.
Ethisterone
Ethisterone is a progestogen hormone being considered to treat prostate cancer.