Chemical
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- Catálogos PDF
Chemical Hay 28543 productos.
Licochalcone D
Licochalcone D is a potent inhibitor of NF-kappaB (NF-κB) p65 with antioxidant, anti-inflammatory, anti-cancer properties.
Harpagoside
Harpagoside was separated from Harpagophytum procumbens (Hp). Harpagoside inhibited COX-1 and COX-2 activity and NO production.
Setmelanotide
Setmelanotide is a selective agonist of the MC4 receptor, with EC50 values of 0.27 nM and 0.28 nM for human and rat MC4R, respectively.
Quercetin dihydrate
Quercetin dihydrate, a natural flavonoid, is a stimulator of recombinant SIRT1 and a PI3K inhibitor with IC50s of 2.4 μM, 3.0 μM and 5.4 μM for PI3K γ, PI3K δ and PI3K β, respectively.
Pemigatinib
Pemigatinib (INCB054828) is an orally effective, selective FGFR inhibitor with IC50 values of 0.4 nM, 0.5 nM, 1.2 nM, and 30 nM for FGFR1, FGFR2, FGFR3, and FGFR4, respectively.Pemigatinib exhibited anti-tumor activity in mouse xenograft models with FGFR1, FGFR2, or FGFR3-altered human tumors in a mouse xenograft model exhibiting antitumor activity.
Narcissoside
Narcissin (Narcissoside) is a coptidis glycoside that clears ONOO- and sin-1 derived ONOO- with IC50 of 3.5 and 9.6 μM, respectively. It has antioxidant activity.
Risperidone
Risperidone is a serotonin 5-HT2 receptor blocker, P-Glycoprotein inhibitor and potent dopamine D2 receptor antagonist, with Kis of 4.8, 5.9 nM for 5-HT2A and dopamine D2 receptor, respectively.
Ensulizole
Ensulizole (PBSA) is a water-soluble sunscreen, a sulfonated UV absorber characterized by strong absorption of UVB and partial absorption of UVA. Ensulizole can damage DNA by producing reactive oxygen species (ROS) when exposed to ultraviolet or sunlight.
LY3039478
LY3039478 (Crenigacestat) is a novel and orally active Notch and γ-secretase inhibitor, with an IC50 of 1 nM in most of the tumor cell lines tested.
Methoxamine hydrochloride
Methoxamine is an α1-adrenergic receptor agonist, it induces vasoconstriction of skin and splanchnic blood vessels.
Trapidil
Terapidil is an antiplatelet compound that partially acts as a competitive inhibitor of phosphodiesterase inhibitors and platelet-derived growth factor (PDGF) receptors.
Amodiaquin dihydrochloride dihydrate
Amodiaquine is a potent, non-competitive inhibitor of histamine N-methyl transferase in human erythrocytes, also used as an antimalarial and anti-inflammatory agent.