Monoethyl Phthalate is a metabolite of diethyl phthalate that acts as an agonist for estrogenic compounds and PPARγ at lower concentrations.
Acetohydroxamic acid is an Urease Inhibitor. In the urine, it acts as an antagonist of the bacterial enzyme urease.
XL413 (BMS-863233) hydrochloride is a potent, selective and ATP competitive inhibitor of Cdc7, with an IC50 of 3.4 nM, and also shows potent effect with IC50s of 215, 42 nM on CK2, PIM1, respectively, and an EC50 of 118 nM on pMCM.
Etrumadenant (AB928, A2aR/A2bR antagonist-1) is an orally bioavailable, dual antagonist of the A2aR and A2bR adenosine receptors, leads to greater immunomodulatory activity and reduced tumor growth.
ALC-0159 is a lipid conjugate of polyethylene glycol that can be used as an excipient for vaccines.
Phytic acid is the principal storage form of phosphorus in many plant tissues, especially bran and seeds. It can act as a cofactor in DNA repair by nonhomologous end-joining.
Ro 31-8220 is a protein kinase C inhibitor, with activity at other protein kinases (IC50 values are 33, 3, 8, 15 and 38 nM for PKCα, MAPKAP-K1b, MSK1, GSK3β and S6K1 respectively).
Sultamicillin Tosylate is a semi-synthetic β-lactamase inhibitor with an IC50 of 0.8 μM.
AMG 337 is an oral, small molecule, ATP-competitive, highly selective inhibitor of the MET receptor.
Ninerafaxstat trihydrochloride shifts cellular metabolism to glucose oxidation from fatty acid oxidation. Ninerafaxstat trihydrochloride improves overall mitochondrial respiration and reduces fatty acid oxidation, thereby inhibiting the proliferation and growth of cancer cells.