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- Catálogos PDF
Chemical Hay 28543 productos.
Escitalopram Oxalate
Escitalopram Oxalate is a selective serotonin (5-HT) reuptake inhibitor (SSRI) with Ki of 0.89 nM.
9-cis-Retinoic Acid
9-cis-Retinoic acid (ALRT1057), a derivative of vitamin A, is a potent RAR/RXR agonist. 9-cis-Retinoic acid induces apoptosis, regulates the cell cycle and has anticancer, anti-inflammatory and neuroprotective activities.
Lucidenic-acid-D
Lucidenic acid D (Lucidenic acid D2) is a highly oxidized lanosterane triterpenoid.
Lucidenic-acid-B
Lucidenic acid B is a natural product isolated from Ganoderma lucidum, which can induce tumor cell apoptosis, activation of caspase-9 and caspase-3, and cleavage of PARP. Lucidenic acid B had no effect on cell cycle and no effect on necrotic cells.
Adezmapimod (SB203580)
Adezmapimod (SB203580) is a P38 MAPK inhibitor with an IC50 of 0.3-0.5 μM, which is 10 times less selective than SAPK3(106T) and SAPK4(106T), and inhibits PKB phosphorylation with an IC50 of 3-5 μM.
Flumazenil
Flumazenil is a competitive GABAA receptor antagonist, used in the treatment of benzodiazepine overdoses.
BDTX-1535
BDTX-1535 (EGFR-IN-76) is a potent inhibitor of EGFR.
UNC1999
UNC1999 is a potent, orally bioavailable and selective inhibitor of EZH2 and EZH1 with IC50 of 2 nM and 45 nM, respectively, showing >1000-fold selectivity over a broad range of epigenetic and non-epigenetic targets.
HA14-1
HA14-1 is a Bcl-2 inhibitor that is widely used for studies of apoptosis with IC50 of ~9 μM.
VHL Ligand 1 hydrochloride
VHL Ligand 1 hydrochloride is the VH032-based VHL ligand used in the recruitment of the von Hippel-Lindau (VHL) protein.
Pleuromutilin
Pleuromutilin is an antibiotic natural product that inhibits bacterial protein synthesis by binding to bacterial ribosomes in the peptidyl transferase center and inhibiting peptide bond formation.
Vimseltinib
Vimseltinib (DCC-3014) is a highly selective, orally active inhibitor of colony-stimulating factor-1 receptor (CSF-IR) and c-Kit with IC50 values of