LX-1031 is a potent, orally available tryptophan 5-hydroxylase (TPH) inhibitor that reduces serotonin (5-HT) synthesis peripherally.
BI-4924 is a lipophilic, highly plasma protein bound selective phosphoglycerate dehydrogenase (PHGDH) inhibitor (IC50=3 nM) with excellent microsomal, as well as hepatocytic stability.
BI-4924 is a lipophilic, highly plasma protein bound selective phosphoglycerate dehydrogenase (PHGDH) inhibitor (IC50=3 nM) with excellent microsomal, as well as hepatocytic stability.
Bimosiamose (TBC-1269) is a nonoligosaccharide pan-selectin antagonist with IC50s of 88 μM, 20 μM, and 86 μM for E-selectin, P-selectin, and L-selectin, respectively. Bimosiamose has anti-inflammatory effects.
Bimosiamose (TBC-1269) is a nonoligosaccharide pan-selectin antagonist with IC50s of 88 μM, 20 μM, and 86 μM for E-selectin, P-selectin, and L-selectin, respectively. Bimosiamose has anti-inflammatory effects.
MELK-8a hydrochloride is a novel maternal embryonic leucine zipper kinase (MELK) inhibitor with an IC50 of 2 nM.
CCT128930 hydrochloride is a potent and selective inhibitor of AKT (IC50=6 nM).
α-CGRP (mouse, rat) (TFA) is a neuropeptide (calcitonin gene-related peptide) that can be used in cardiovascular, proinflammatory, and metabolic studies. Sequence: SCNTATCVTHRLAGLLSRSGGVVKDNFVPTNVGSEAF - NH2 (Disulfide bridge: Cys2 - Cys7)
α-CGRP (mouse, rat) (TFA) is a neuropeptide (calcitonin gene-related peptide) that can be used in cardiovascular, proinflammatory, and metabolic studies. Sequence: SCNTATCVTHRLAGLLSRSGGVVKDNFVPTNVGSEAF - NH2 (Disulfide bridge: Cys2 - Cys7)
Oleandrigenin is a metabolite and an Na(+)/K(+)-transporting ATPase inhibitor. Oleandrigenin is a steroid ester that is the 16-acetyl derivative of gitoxigenin.