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Chemical Hay 28543 productos.
2-Aminoethyl diphenylborinate (2-APB)
2-Aminoethyl diphenylborinate (2-APB) is a cell-permeable inhibitor of IP3R, and regulate IP3-induced calcium release. 2-Aminoethyl diphenylborinate also inhibits the store-operated Ca2+ (SOC) channel and activates some TRP channels (V1, V2 and V3).
TM5441
TM5441 is an orally bioavailable inhibitor of plasminogen activator inhibitor-1 (PAI-1), with IC50 values between 13.9 and 51.1 μM against several human cancer cell lines.
TM5441
TM5441 is an orally bioavailable inhibitor of plasminogen activator inhibitor-1 (PAI-1), with IC50 values between 13.9 and 51.1 μM against several human cancer cell lines.
TM5441
TM5441 is an orally bioavailable inhibitor of plasminogen activator inhibitor-1 (PAI-1), with IC50 values between 13.9 and 51.1 μM against several human cancer cell lines.
TM5441
TM5441 is an orally bioavailable inhibitor of plasminogen activator inhibitor-1 (PAI-1), with IC50 values between 13.9 and 51.1 μM against several human cancer cell lines.
Tetramethylrhodamine ethyl ester perchlorate
Tetramethylrhodamine ethyl ester (TMRE) can bind to mitochondria and produce orange fluorescence with a maximum excitation/emission wavelength of 550nm/576nm, which is often used to observe mitochondria. Store in refrigerator (-5 to -30°C) away from light.
CU-CPT-9a
CU-CPT-9a is a potent TLR8 antagonist with IC50 of 0.5 nM, which that suppresses TLR8-mediated proinflammatory signaling in various cell lines and human primary cells.
2-D08
2-D08 is a cell permeable, mechanistically unique inhibitor of protein SUMOylation. 2-D08 also inhibits Axl with an IC50 of 0.49 nM.
E3 ligase Ligand 1
E3 ligase Ligand 1 (VHL ligand 2 hydrochloride; (S,R,S)-AHPC-Me hydrochloride) is the (S,R,S)-AHPC-based VHL ligand used in the recruitment of the von Hippel-Lindau (VHL) protein.
Lixumistat
Lixumistat (IM156) is a novel biguanide mitochondrial protein complex 1 inhibitor of oxidative phosphorylation (OXPHOS) with anti-tumor activity. Lixumistat regulates OXPHOS to attenuate mitochondrial metabolic reprogramming and inhibit lung fibrosis. Lixumistat (IM156) is a metformin derivative, which increases AMPK phosphorylation.
CDKI-73
Cdki-73 (LS-007) is an orally active and highly effective CDK9 inhibitor with Ki values of 4 nM, 4 nM and 3 nM against CDK9, CDK1 and CDK2, respectively. Cdki-73 down-regulates phosphorylation of RNA polymerase II. Cdki-73 is also an inhibitor of Rab11.
tert-Butyl hydroperoxide
Tert-butyl Hydroperoxide, referred to as TBHP, is one of the most commonly used alkyl hydrogen organic peroxides.