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    • MTK458 is an orally active, brain-permeable PINK1 activator that binds to and stabilizes the active isoform of PINK1, thereby enhancing mitophagy and promoting mitochondrial autophagy (Mitophagy). It can be used in studies related to Parkinson's disease (PD).

    • Trofinetide, a water-soluble analog of glycine-proline-glutamic acid (GPE), uses the unnatural amino acid 2-methylproline in place of the proline found in the natural compound, and works by enhancing synaptic activity, restoring synaptic structure, inhibiting the effects of inflammatory compounds in the brain, increasing antioxidant responses, reducing...

    • Trofinetide, a water-soluble analog of glycine-proline-glutamic acid (GPE), uses the unnatural amino acid 2-methylproline in place of the proline found in the natural compound, and works by enhancing synaptic activity, restoring synaptic structure, inhibiting the effects of inflammatory compounds in the brain, increasing antioxidant responses, reducing...

    • Saralasin TFA is an octapeptide analog of Angiotensin II and a competitive angiotensin II receptor antagonist with a Ki value of 0.32 nM (74% of binding sites) and partial agonist activity. It has a Ki value of 0.32 nM (74% of binding sites) and partial agonist activity. It can be used in studies related to renal vascular hypertension and renin-dependent...

    • Saralasin TFA is an octapeptide analog of Angiotensin II and a competitive angiotensin II receptor antagonist with a Ki value of 0.32 nM (74% of binding sites) and partial agonist activity. It has a Ki value of 0.32 nM (74% of binding sites) and partial agonist activity. It can be used in studies related to renal vascular hypertension and renin-dependent...

    • Ac-Arg-Gly-Lys(Ac)-AMC acetate is a substrate for histone deacetylase (HDAC) and can be used in a novel fluorescent assay for HDAC activity.

    • Ac-Arg-Gly-Lys(Ac)-AMC acetate is a substrate for histone deacetylase (HDAC) and can be used in a novel fluorescent assay for HDAC activity.

    • BPC 157 is a stable gastric pentadecapeptide and a partial sequence of the human gastric juice protein BPC.

    • BPC 157 is a stable gastric pentadecapeptide and a partial sequence of the human gastric juice protein BPC.

    • Isolinderalactone suppresses human glioblastoma growth and angiogenic activity through the inhibition of VEGFR2 activation in endothelial cells. Isolinderalactone suppressed the expression of B-cell lymphoma 2 (BCL-2), as well as of survivin and X-linked inhibitor of apoptosis protein (XIAP).

    • Isolinderalactone suppresses human glioblastoma growth and angiogenic activity through the inhibition of VEGFR2 activation in endothelial cells. Isolinderalactone suppressed the expression of B-cell lymphoma 2 (BCL-2), as well as of survivin and X-linked inhibitor of apoptosis protein (XIAP).

    • Mitoguazone is a brain-penetrant and competitive S-adenosyl-methionine decarboxylase (SAMDC) inhibitor that disrupts polyamine biosynthesis. Mitoguazone induces cell apoptosis. Mitoguazone inhibits HIV DNA integration into the cellular DNA in both monocytes and macrophages.

    Mostrando 25237 a 25248 de 28543 productos