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Chemical Hay 28543 productos.
Articaine hydrochloride
Articaine hydrochloride is a dental local anesthetic which contains an additional ester group that is metabolized by estearases in blood and tissue. Articaine hydrochloride ameliorates LPS-induced acute kidney injury via inhibition of NF-ĸB activation and the NLRP3 inflammasome pathway.
TCS-OX2-29
TCS-OX2-29 is a potent, high affinities and selective orexin-2 receptor (OX2R) antagonist with an IC50 value of 40 nM and a pKI value of 7.5. TCS-OX2-29 displays ~250-fold selectivity for OX2 over OX1.
Fluocinolone Acetonide
Fluocinolone Acetonide is a corticosteroid that binds to the cytosolic glucocorticoid receptor.
Necroptosis-IN-3
Necroptosis-IN-3, an inhibitor of necroptosis, inhibits TNF-α-induced necroptosis and also inhibits 11β-HSD1.
SF 1670
SF 1670 is a pTPN2 and PTEN inhibitor.
D-Cellobiose octaacetate
D-Cellobiose octaacetate
CY-09
CY-09 is a selective direct inhibitor of NLRP3 with anti-inflammatory and antidepressant activity, which inhibits inflammatory cytokine production and TRPA1 activation by inhibiting the activation of the NLRP3 inflammatory vesicle, thereby decreasing the intracellular Ca2+ level and reducing the pro-inflammatory polarization of macrophages, alleviating...
Mitoxantrone
Mitoxantrone is a type II topoisomerase inhibitor with IC50 of 2.0 μM, 0.42 mM for HepG2 and MCF-7/wt cells, respectively
EPZ020411
EPZ020411 is a potent and selective inhibitor of PRMT6 with IC50 of 10 nM, has ＞10 fold selectivity for PRMT6 over PRMT1 and PRMT8.
Myricetrin
Myricitrin is a major antioxidant.
AZ084
AZ084 is a potent, selective, allosteric and oral active CCR8 antagonist, with a Ki of 0.9 nM. Has potential to treat asthma.
Sorafenib Tosylate
Sorafenib (BAY 43-9006) Tosylate is an orally active multikinase inhibitor of tyrosine protein kinases VEGFR/PDGFR and RAF/MEK/ERK with IC50 values of 6, 22, 38 nM for Raf-1, wt BRAF and V599E mutant BRAF.