NT-0796 is an isopropyl ester that is converted intracellularly to NDT-197959 and is also a selective, CNS-transmitting NLRP3 inhibitor with an IC50 of 0.32 nM in PBMC.May be used in studies related to neuroinflammatory diseases.
NLRP3/AIM2-IN-2 is a novel potent inhibitor with different species-specific effects on NLRP3 and AIM2 inflammasome-dependent cellular pyroptosis, with an IC50 value of 0.2392 ± 0.0233 μM.
NLRP3/AIM2-IN-2 is a novel potent inhibitor with different species-specific effects on NLRP3 and AIM2 inflammasome-dependent cellular pyroptosis, with an IC50 value of 0.2392 ± 0.0233 μM.
NLRP3/AIM2-IN-2 is a novel potent inhibitor with different species-specific effects on NLRP3 and AIM2 inflammasome-dependent cellular pyroptosis, with an IC50 value of 0.2392 ± 0.0233 μM.
NLRP3/AIM2-IN-2 is a novel potent inhibitor with different species-specific effects on NLRP3 and AIM2 inflammasome-dependent cellular pyroptosis, with an IC50 value of 0.2392 ± 0.0233 μM.
Plecanatide acetate is an analog of urinary guanosine protein and an orally active guanylate cyclase-C (GC-C) receptor agonist with an EC50 value of 190 nM in T84 cells.Additionally, Plecanatide acetate has been shown to have anti-inflammatory activity and can be used in studies related to chronic idiopathic constipation. In addition, Plecanatide acetate...
Plecanatide acetate is an analog of urinary guanosine protein and an orally active guanylate cyclase-C (GC-C) receptor agonist with an EC50 value of 190 nM in T84 cells.Additionally, Plecanatide acetate has been shown to have anti-inflammatory activity and can be used in studies related to chronic idiopathic constipation. In addition, Plecanatide acetate...
TRV056 is a Gq-biased ligand of the angiotensin II receptor type 1 (AT1R). TRV056 is efficacious in stimulating cellular Gq-mediated signaling. TRV056 can be used to develop the Gq-biased AT1R agonists.
TRV056 is a Gq-biased ligand of the angiotensin II receptor type 1 (AT1R). TRV056 is efficacious in stimulating cellular Gq-mediated signaling. TRV056 can be used to develop the Gq-biased AT1R agonists.
Trilaurin is used in cosmetic products as thickening agents and emollients. Trilaurin could inhibit the formation of neoplasms initiated by dimethylbenzanthracene (DMBA) and promoted by croton oil.
DBCO-acid is a cleavable ADC linker used in the synthesis of ADC linker DBCO-NHS ester, and agent-linker conjugates DBCO-PEG-MMAE.
Myosin H Chain Fragment, mouse acetate salt is a fragment of the α-Myosin heavy chain peptide. Myosin H Chain Fragment can be used to induce experimental autoimmune myocarditis (EAM) mouse model.