Rilutek is a sodium channel protein inhibitor and a new mental compound, which has anticonvulsant, hypnotic, antianxiety, antiischemia and anesthesia properties. Riluzole belongs to the family of use-dependent Na+ channel blocker which can also inhibit GABA uptake with an IC50 of 43 μM.
NVP-TNKS656 is a highly potent, selective, and orally active TNKS2 inhibitor with IC50 of 6 nM; > 300 fold selectivity against PARP1 and PARP2.
NX-5948 (BTK-IN-24) is an orally active, blood-brain barrier-penetrating, BTK-targeting degradation agent for the study of B-cell malignancies and autoimmune diseases. NX-5948 induces specific BTK protein degradation by the cereblon E3 ligase (CRBN) complex without degradation of other cereblon neo-substrates. NX-5948 mediates potent anti-inflammatory...
1,5-Dihexadecyl N-(3-carboxy-1-oxopropyl)-L-glutamate is a lipid that can be used in the synthesis of phospholipid vesicles to improve protein encapsulation.
NCC007 is a dual casein kinase Iα (CKIα) and δ (CKIδ) inhibitor with IC50s of 1.8 and 3.6 μM, respectively. NCC007 can be used in research of modulating mammalian circadian rhythms.
Wu-5 is a USP10 inhibitor that can inhibit FLT3 and AMPK pathways, induce FLT3-ITD degradation and induce apoptosis.
Behenamide is a nonionic surfactant that is stable in acidic, alkaline and aqueous media and can be used as a biomaterial or organic compound for life science related research.
Fluoxetine (LY-110140 free base) is a selective serotonin reuptake inhibitor (SSRI) class used for antidepressant research.
Methylprednisolone sodium succinate is a glucocorticoid receptor agonist with immunosuppressive and anti-inflammatory activity that can be converted to active prednisolone in vivo, thereby activating GR-mediated gene expression. In addition, Methylprednisolone sodium succinate can be used to construct a rat model of hormonal femoral head necrosis.
Tanshinol B is a bioactive component of Salvia miltiorrhiza, which can be isolated from the 50% ethanol extract of the roots and rhizomes of Seaweed prowazekii.
Lauflumide is the common alternative of modafinil. Modafinil is commonly prescribed for the research narcolepsy.
Metyrosine is a selective tyrosine hydroxylase enzyme inhibitor. Metyrosine significantly inhibits high COX-2 activity. Metyrosine exerts anti-inflammatory and anti-ulcerative effects.