Chemical
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- Catálogos PDF
Chemical Hay 28543 productos.
Dac51
Dac51 is an effective FTO inhibitor with an IC50 of 0.4 μM against FTO demethylation.
Vitamin E succinate
Vitamin E succinate is a derivative of Vitamin E, VES can block tumor cell cycle in G1 phase, promote tumor cell differentiation and inhibit tumor Cell DNA synthesis, increase the secretion and activation of transfer growth factor β (TGF-β).
Coppersensor 1
Coppersensor-1 is a membrane-permeable fluorescent dye. Coppersensor-1 has a picomolar affinity for Cu+ with high selectivity over competing cellular metalions. Coppersensor-1 as a probe, can selective and sensitive detection of copper(I) ions (Cu+) in biological samples, including live cells.
Temuterkib
Temuterkib (LY3214996) is a selective, novel erK1/2 inhibitor with an IC50 of 5 nM against ERK1 and ERK2. It can effectively inhibit intracellular P-RSK1 in cancer cell lines with BRAF and RAS mutations. Temuterkib has strong antitumor activity in cancer models with altered MAPK pathways.
Aloxistatin
Aloxistatin (E64d) is an irreversible and membrane-permeable cysteine protease inhibitor.
BI-847325
BI-847325 is an orally bioavailable, and selective dual MEK/Aurora kinase inhibitor with IC50 of 3 nM, 25 nM, 15 nM, 25 nM, and 4 nM for Xenopus laevis Aurora B, human Aurora A and Aurora C, as well as human MEK1 and MEK2, respectively.
I-BET-762
I-BET-762 (GSK525762) is a selective small molecule BET inhibitor.
Dofequidar fumarate
Dofequidar fumarate(MS-209 fumarate), an orally active quinoline compound, has been reported to overcome MDR by inhibiting ABCB1/P-gp, ABCC1/MDR-associated protein 1, or both.
(-)-Epigallocatechin gallate
(-)-Epigallocatechin Gallate is an antioxidant polyphenol flavonoid form green tea, and inhibits the activation of EGFR, HER2 and HER3, with antitumor activity.
NAcM-OPT
NAcM-OPT is a specific, reversible and orally bioavailable inhibitor of cullin neddylation 1 (DCN1) that targets N-Acetyl-UBE2M (E2 conjugating enzyme, UBC12) interaction with DCN1 with IC50 of 79 nM.
Icotinib
Icotinib (BPI-2009H) is a potent and novel epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) with an IC50 of 5 nM. Iconitib inhibits the proliferation of A431 and BGC-823 A549, H460 and KB cell lines with IC50s of 1, 4.06, 12.16, 16.08, 40.71 μM.
Milrinone
Milrinone is a potent and selective phosphodiesterase 3 inhibitor with an IC50 of 0.42 μM for the inhibition of FIII PDE.