Chemical
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Chemical Hay 28543 productos.
Benzamide
Benzamide is an inhibitor of poly(ADP-ribose) polymerase with an IC50 of 3.3 μM.
HS-173
HS-173 is a potent PI3Kα inhibitor with IC50 of 0.8 nM.
SKF-34288 hydrochloride
SKF-34288 (3-Mercaptopicolinic acid) hydrochloride is an orally active phosphoenolpyruvate carboxykinase (PEPCK) inhibitor (Ki = 2-9 μM). SKF-34288 hydrochloride is a potent hypoglycemic agent by inhibiting glucose synthesis.
Firibastat
Firibastat (QGC001) is an orally active EC33 precursor drug. Firibastat is A first-in-class (first-in-class) brain aminopeptidase A (APA) inhibitor (Ki=200 nM) that selectively and specifically inhibits the conversion of cerebral angiotensin II to angiotensin III and lowers blood pressure in hypertensive rats.
BAY 61-3606 dihydrochloride
BAY-61-3606 is a potent and selective inhibitor of Syk kinase (Ki = 7.5 nM).
AMG-510 racemate
AMG-510 racemate is a racemic of AMG-510, which is a potent KRAS G12C covalent inhibitor.
Tropifexor
Tropifexor is a novel and highly potent agonist of farnesoid X receptor (FXR).
GNF-6231
GNF-6231 is a strong, selective, oral-capable Porcupine inhibitor capable of blocking the Wnt signaling pathway.
ABT-888
ABT-888 (Veliparib) is a potent inhibitor of PARP-1 and PARP-2 with Ki values of 5.2nM and 2.9nM respectively.
CG347B
CG347B is a selective HDAC6 inhibitor.
LY-3381916
LY-3381916 (IDO1-IN-5) is a potent IDO1 inhibitor that can penetrate the blood brain barrier. LY-3381916 May show antitumor activity.
N-Glycolylneuraminic acid
N-Glycolylneuraminic acid is a nonhuman sialic acid molecule synthesized in pigs but not in humans. N-Glycolylneuraminic acid works as a decoy receptor of N-Glycolylneuraminic acid-binding influenza A viruses (IAVs).