Chemical
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- Catálogos PDF
Chemical Hay 28543 productos.
Riluzole
Rilutek is a sodium channel protein inhibitor and a new mental compound, which has anticonvulsant, hypnotic, antianxiety, antiischemia and anesthesia properties. Riluzole belongs to the family of use-dependent Na+ channel blocker which can also inhibit GABA uptake with an IC50 of 43 μM.
Givinostat
Givinostat (ITF-2357) is an HDAC inhibitor with IC50s of 198 and 157 nM for HDAC1 and HDAC3, respectively.
GM6001
GM6001 (Galardin, Ilomastat) is a broad-spectrum matrix metalloproteinase inhibitor.
AGN 193109
AGN 193109 is a high affinity pan-RAR antagonist.
MMAD
Monomethyl auristatin D (MMAD), a potent tubulin inhibitor, is a toxin payload in antibody compound conjugate.
GW 1929 hydrochloride
GW 1929 hydrochloride is a selective PPARγ agonist. Orally active.
Sertindole
Sertindole, a neuroleptic, is one of the newer antipsychotic medications available.
Leukadherin-1
Leukadherin-1 is a allosteric activator of CD11b/CD18. Leukadherin-1 increases CD11b/CD18-dependent cell adhesion to fibrinogen with an EC50 of 4 μM.
β-Galactosidase
β-Galactosidase is a glycoside hydrolase that hydrolyzes the β-glycosidic bond formed between galactose and its organic part. In Escherichia coli, the lacZ gene is the structural gene for β-galactosidase and can be used as part of the lac manipulator of the inducible system. β-Galactosidase hydrolyzes lactose to form glucose and galactose, which enter...
Ciwujianoside C3
Ciwujianoside C3 is an orally active and brain penetrated compound, which is isolated the leaves of Acanthopanax henryi Harms. Ciwujianoside C3 has anti-inflammatory effect and can reinforces object recognition memory.
Zoliflodacin
Zoliflodacin (ETX0914;AZD0914) is a novel spiropyrimidinetrione bacterial DNA gyrase/topoisomerase inhibitor. Zoliflodacin has potent in vitro antibacterial activity against Gram-positive and Gram-negative organisms, including S. aureus with the MIC90 of 0.25 μg/mL.
IACS-13909
IACS-13909 is a potent selective, orally active SHP2 allosteric inhibitor IC50 for 15.7 nM,Kd 32 nM. IACS-13909 is more selective for SHP2 than other phosphatase, including SHP1. IACS-13909 inhibits the signaling of the receptor tyrosine kinase (RTK)/MAPK pathway and has an anticancer effect.