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- Catálogos PDF
Chemical Hay 28543 productos.
Nodosin
Nodosin is a diterpenoid isolated from Isodon trichocarpus Kudo and I. Japonicus HARA.
XP-59
XP-59 is a potent inhibitor of the SARS-CoV Mpro, with a Ki of 0.1 μM.
Trabectedin
Trabectedin (Ecteinascidin 743; ET-743) is a tetrahydroisoquinoline alkaloid that binds to the minor groove of DNA, blocks stress-induced transcription of proteins, induces DNA backbone cleavage and apoptosis, and increases ROS production in MCF-7 and MDA-MB-453 cells. Trabectedin can be used in soft tissue sarcoma and ovarian cancer studies.
Noladin ether
Noladin ether is a potent and selective agonist of cannabinoid CB1 receptor, with a Ki of 21.2 nM.
Carbetocin acetate
Carbetocin acetate is an oxytocin (OT) analog and oxytocin receptor agonist that crosses the blood-brain barrier with a Ki of 7.1 nM. In addition, Carbetocin acetate has a high affinity for the chimeric N-terminal (E1) end of the oxytocin receptor, with a Ki = 1.17 μM. Carbetocin acetate can be used in studies related to postpartum hemorrhage.
Fluzoparib (SHR3162)
Fluzoparib (SHR3162) is an effective oral active PARP1 inhibitor (IC50=1.46±0.72 nM) with superior antitumor activity. Fluzoparib selectively inhibited the proliferation of homologous recombination repair (HR) deficient cells and sensitized HR deficient cells to cytotoxic drugs. Fluzoparib has good pharmacokinetic properties in vivo and can be used in...
ICG-amine
ICG-amine (ICG-NH2) is a near-infrared fluorescent probe, binds to amino acid residues without condensing agents.
GS 143
GS 143 is a β-TrCP1 ligase inhibitor.
Mdivi-1
Mdivi-1 is a selective cell-permeable inhibitor of mitochondrial division DRP1 (dynamin-related GTPase) and mitochondrial division Dynamin I (Dnm1) with IC50 of 1-10 μM.
Daprodustat
Daprodustat (GSK1278863) is a novel, first-in-class, orally active inhibitor of hypoxia-induced factor prolyl hydroxylase (HIF-PHI). Reversible inhibition of HIF-PHD activity under normal partial oxygen pressure can temporarily inhibit HIF-α degradation and promote the expression of related hypoxia metabolism genes.
BMS-986020
BMS-986020 (also known as AM152) is a potent and selective LPA1 antagonist.
Hydroxy Itraconazole
Itraconazole metabolite Hydroxy Itraconazole is an active metabolite of Itraconazole (ITZ), which is a triazole antifungal agent.