Duvelisib (IPI-145) is a potent, oral inhibitor of phosphoinositide-3-kinase (PI3K)-delta and PI3K-gamma.
Hederacoside C (HDC) is one of the active ingredients in Hedera helix leaf extract (Ivy Ex.)
Norepinephrine is generally considered to be a β1-selective adrenergic receptor agonist with EC50 of 5.37 μM.
Bilastine is a selective histamine H1 receptor antagonist used for treatment of allergic rhinoconjunctivitis and urticaria.
Jsh-23 is a NF-κB inhibitor, inhibited NF-κB transcriptional activity in lipopolysaccharid-stimulated macrophages RAW 264.7 with IC50 of 7.1 μM. Jsh-23 inhibited the nuclear translocation of NF-κB P65 without affecting the degradation of IκBα.
Cyclohexanecarboxylic acid is a Valproate structural analogue with anticonvulsant action.
Riociguat (BAY 63-2521) is an oral soluble guanylate cyclase (GC) stimulator, used in the research of ipulmonary hypertension.
PHA-680632 is potent inhibitor of Aurora A, Aurora B and Aurora C with IC50 of 27 nM, 135 nM and 120 nM, respectively. It has 10- to 200-fold higher IC50 for FGFR1, FLT3, LCK, PLK1, STLK2, and VEGFR2/3.
Neobavaisoflavone, a flavonoid, is isolated from the seeds of Psoralea corylifolia.
TR-14035 is an orally active α4b7/a4b1 integrins (a4b7/a4b1 integrindual inhibitors, for α4b7 和 a4b1 function IC50 The values are 7 nM and 87 nM, respectively. TR-14035 can be used for the study of inflammatory and autoimmune diseases.