Clofibric acid (PCIB, Chlorofibrinic acid), a lipid fiber modulator Clofibrate, Etofibrate and Etofyllinclofibrate active metabolites, is a PPARα excitant, has the effect of lowering blood lipid. Clofibric acid is also a herbicide.
Salicylic acid is a beta hydroxy acid that occurs as a natural compound in plants which is an inhibitor of ethylene biosynthesis and cyclooxygenase activity.
Ginsenoside Rg6 inhibited NF-κB transcriptional activity induced by TNF-α in HepG2 cells with IC50 of 29.34 μM. Ginsenoside Rg6 also induced apoptosis.
Pralsetinib (BLU-667) is a next generation highly potent, selective RET inhibitor with IC50 of 0.3-0.4 nM for WT RET, RET mutants V804L, V804M, M918T and CCDC6-RET fusion.
ATN-161 TFA salt is a novel small peptide inhibitor of integrin α5β1; a beta integrin antagonist with antitumor activity.
Thymosin alpha 1 (Thymalfasin) is an immunomodulating agent able to enhance the Thl immune response.
(20S)-Protopanaxadiol (aPPD) is one of the aglycones of the ginsenosides and has a wide range of pharmacological activities.
AT2 receptor agonist C21 is a druglike selective angiotensin II AT2 receptor agonist with Ki values of 0.4 nM and >10 µM for the AT2 receptor and AT1 receptor, respectively.
Cyclohexanecarboxylic acid is a Valproate structural analogue with anticonvulsant action.