Dipiramide (DISO) is a class 1A antiarrhythmic compound widely used in the study of ventricular and supraventricular arrhythmias.
Hoechst 34580 (HOE 34580) is related to important small furrow binding dsDNA selective dyes Hoechst 33258 and Hoechst 33342, with a maximum excitation/emission wavelength of 392nm/440 nm (after binding to DNA), emitting blue fluorescence. For observation of nuclei, nucleic acids, stored at -25°C, away from light.
Dispase is a neutral proteinase from microorganisms and is useful for cell isolation and tissue dissociation.
Atglistatin is a highly potent, and selective inhibitor of adipose triglyceride lipase (ATGL) with IC50 of 0.7 μM, high selectivity over other key metabolic lipases.
AMG-458 is a potent, selective and orally bioavailable c-Met inhibitor, with Ki values of 1.2 nM and 2.0 nM for human and mouse c-Met, respectively.
12-Ketodeoxycholic acid is a bile acid, metabolite from kidney. 12-Ketodeoxycholic acid can be a detectable marker for evidence of kidney injury.
Bohemine is A selective CDK inhibitor with IC50 of 4.6 μM, 83 μM and 2.7 μM against Cdk2/ Cyclin E, Cdk2/ Cyclin A and Cdk9/cyclin T1, respectively. Bohemine also inhibited ERK2, IC50 was 52 μM, and inhibited CDK1, CDK4 and CDK6. Bohemine is also a purine analogue and has a wide range of anticancer activities.
Hydroxy-α-sanshool is a transient receptor potential ankyrin 1 (TRPA1) and TRP vanilloid 1 (TRPV1) agonist with EC50s of 69 and 1.1 µM, respectively.
17-Hydroxyisolathyrol is a macrocychc lathyrol derivative isolated from seeds of Euphorbla luthyrrs.