Betamethasone Valerate is a moderately potent glucocorticoid steroid with anti-inflammatory and immunosuppressive properties.
Jc-1 (Mitochondrial membrane potential probe) is a fluorescent lipophilic carbonyl cyanine dye used to measure mitochondrial membrane potential. The maximum excitation/emission wavelength is 515nm/529nm (590nm), and green fluorescence is emitted. Used to observe mitochondria, stored at room temperature, away from light.
BIBF 1120 esylate is a potent triple angiokinase inhibitor for VEGFR1/2/3, FGFR1/2/3 and PDGFRα/β with IC50s of 34 nM/13 nM/13 nM, 69 nM/37 nM/108 nM and 59 nM/65 nM, respectively.
LX2343 is a BACE1 enzyme inhibitor with IC50 value of 11.43±0.36 μM, and it is a neuroprotective agent.
AZD5462 is a RXFP1 modulator, can be used for heart failure research. RXFP1 is the cognate receptor for human relaxin, belongs to GPCR family 1c number with anti-fibrotic and anti-inflammatory properties.
Trimetazidine is a selective long chain 3-ketoyl coenzyme A thiolase inhibitor with an IC50 of 75 nM, which can inhibit β-oxidation of free fatty acid (FFA).
Murrayafoline A is a carbazole alkaloid that enhances calcium inward flow through L-type calcium channels.Murrayafoline A can be used for related research in the life sciences.
Butyrolactone 3 (MB-3) is a specifical small-molecule inhibitor of the histone acetyltransferase Gcn5 (IC50=100 μM), which has a high affinity to the Gcn5 enzyme comparable to that of its natural substrate, histone H3.
SB-743921 is a highly potent and active KSP inhibitor with a Ki of 0.1 nM for KSP (Eg5).
Ligustilide is a bioactive phthalate derivative isolated from Angelica sinensis and Ligusticum chuanxiong. Ligustilide has neuroprotective, anticancer, anti-inflammatory and vasodilatation effects. *The compound is unstable in solutions, freshly prepared is recommended
Brompheniramine hydrogen maleate is a histamine H1 receptors antagonist.
MPI-0479605 is an ATP competitive and selective inhibitor of mitotic kinase Mps1 with IC50 of 1.8 nM, >40-fold selectivity over other kinases.