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Amarogentin
S-S1273-5mg
Producto nuevo
21018-84-8
Al comprar este producto puede obtener hasta 16 puntos de fidelidad. Su cesta totalizará 16 puntos de fidelidad que se puede(n) transformar en un cupón de descuento de 3.20EUR.
Ficha de datos
| Size | 5mg |
| Target | Moleculas Pequeñas |
| CAS Number | 21018-84-8 |
Más información
Amarogentin (AG), a secoiridoid glycoside mainly extracted from Swertia and Gentiana roots, exhibits anti-oxidative, anti-tumour, and anti-diabetic activities. Amarogentin is an agonist for the bitter taste receptor TAS2R1 and inhibits in LAD-2 cells substance P-induced production of newly synthesized TNF-α. Amarogentin induces apoptosis in human gastric cancer cells (SNU-16) through G2/M cell cycle arrest and PI3K/Akt signalling pathway. Amarogentin (AG) interacts with the α2 subunit of AMP-activated protein kinase (AMPK) and activates the trimeric kinase with EC50 of 277 pM.