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Ginsenoside Rb3
S-S9208-1mg
Producto nuevo
Ginsenoside Rb3
Al comprar este producto puede obtener hasta 17 puntos de fidelidad. Su cesta totalizará 17 puntos de fidelidad que se puede(n) transformar en un cupón de descuento de 3.40EUR.
Ficha de datos
| Size | 1mg |
| Target | Moleculas Pequeñas |
| CAS Number | 68406-26-8 |
| Small Target | NF-κB |
| Pathway | NF-κB |
| Smiles | CC(C)=CCCC(C)(OC1OC(COC2OCC(O)C(O)C2O)C(O)C(O)C1O)C3CCC4(C)C3C(O)CC5C6(C)CCC(OC7OC(CO)C(O)C(O)C7OC8OC(CO)C(O)C(O)C8O)C(C)(C)C6CCC45C |
Más información
Ginsenoside Rb3, extracted from the plant Panax ginseng, plays important roles in cardiovascular diseases, including myocardial ischemia-reperfusion (I/R) injury. Ginsenoside Rb3 (0.1-10 μM) is tested for inhibition of tumor necrosis factor-α (TNF)-induced nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB)luciferase reporter activity using a human kidney 293T cell-based assay. Ginsenoside Rb3 shows the significant activity with an IC50 of 8.2 μM. Ginsenoside Rb3 also inhibits the induction of cyclooxygenase-2 (COX-2)and inducible nitric oxide synthase (iNOS)messenger Ribonucleic acid (mRNA) in a dose-dependent manner after HepG2 cells have been treated with TNF-α (10 ng/mL).