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Rolapitant
S-S5476-5mg
Producto nuevo
552292-08-7
Al comprar este producto puede obtener hasta 13 puntos de fidelidad. Su cesta totalizará 13 puntos de fidelidad que se puede(n) transformar en un cupón de descuento de 2.60EUR.
Ficha de datos
| Size | 5mg |
| Target | Moleculas Pequeñas |
| CAS Number | 552292-08-7 |
| Small Target | Substance P |
| Pathway | Neuronal Signaling |
| Smiles | CC(OCC1(CCC2(CCC(=O)N2)CN1)C3=CC=CC=C3)C4=CC(=CC(=C4)C(F)(F)F)C(F)(F)F |
Más información
Rolapitant (SCH-619734) is a selective and competitive antagonist of human substance P/NK1 receptors with antiemetic activity. It has a high affinity for the human NK1 receptor of 0.66 nM and high selectivity over the human NK2 and NK3 subtypes of >1000-fold, as well as preferential affinity for human, guinea pig, gerbil and monkey NK1 receptors over rat, mouse and rabbit.