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LDN-193189
S-S2618-25mg
Producto nuevo
LDN-193189
Al comprar este producto puede obtener hasta 64 puntos de fidelidad. Su cesta totalizará 64 puntos de fidelidad que se puede(n) transformar en un cupón de descuento de 12.80EUR.
Ficha de datos
| Size | 25mg |
| Target | Moleculas Pequeñas |
| CAS Number | 1062368-24-4 |
| Small Target | TGF-beta/Smad |
| Pathway | TGF-beta/Smad |
Más información
LDN-193189 (DM3189) is a selective BMP signaling inhibitor, inhibits the ALK1, ALK2, ALK3and ALK6with IC50s of 0.8 nM, 0.8 nM, 5.3 nM and 16.7 nM in the kinase assay, respectively. LDN-193189 inhibits the transcriptional activity of the BMP type I receptors ALK2 and ALK3 with IC50s of 5 nM and 30 nM in C2C12 cells, respectively, exhibits 200-fold selectivity for BMP versus TGF-β. For animal testing, the water-soluble S7507 LDN-193189 2HCl is recommended.This product has poor solubility, animal experiments are available, cell experiments please choose carefully!