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Doxorubicin (DOX) HCl
S-S1208-100mg
Producto nuevo
Doxorubicin (DOX) HCl
Al comprar este producto puede obtener hasta 51 puntos de fidelidad. Su cesta totalizará 51 puntos de fidelidad que se puede(n) transformar en un cupón de descuento de 10.20EUR.
Ficha de datos
| Size | 100mg |
| Target | Moleculas Pequeñas |
| CAS Number | 25316-40-9 |
| Small Target | Topoisomerase |
| Pathway | DNA Damage/DNA Repair |
| Smiles | Cl.COC1=C2C(=O)C3=C(C(=C4CC(O)(CC(OC5CC(N)C(O)C(C)O5)C4=C3O)C(=O)CO)O)C(=O)C2=CC=C1 |
Más información
Doxorubicin (DOX) HCl is an antibiotic agent that inhibits human DNA topoisomerase I and topoisomerase II with IC50s of 0.8 μM and 2.67 μM, respectively. Doxorubicin reduces basal phosphorylation of AMPK. Doxorubicin is used in the concomitant treatment of HIV-infected patients but is found to be at high risk of HBV reactivation.This product may precipitate when dissolved in PBS solution. It is recommended to prepare the stock solution in pure water and dilute with either pure water or saline to obtain the working solution.