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Onvansertib
AM-M13718-5mg
Producto nuevo
Onvansertib (PCM-075, NMS-1286937, NMS-P937) is a first-in-class, third-generation, oral, highly selective PLK1 inhibitor that induces tumor cell arrest in the G2/M phase and triggers apoptosis. It has a median IC50=136nM against a variety of CRC cell lines and inhibits xenograft models such as HT-29, HCT-116, and Colo-205 well.
Al comprar este producto puede obtener hasta 7 puntos de fidelidad. Su cesta totalizará 7 puntos de fidelidad que se puede(n) transformar en un cupón de descuento de 1.40EUR.
Ficha de datos
| Size | 5mg |
| Molecular Weight | C24H27F3N8O3 |
| Research Area | PLK |
| CAS Number | '1034616-18-6 |
| Smiles | CN1CCN(CC1)C2=CC=C(OC(F)(F)F)C(=C2)NC3=NC4=C(CCC5=C4[N](CCO)N=C5C(N)=O)C=N3 |