Vincamine

Vincamine can be used as a peripheral vascular dilator (Vasodilator) to selectively regulate cerebral microvascular circulation. Vincamine is a GPR40 agonist that plays a beta-cell protective role by improving beta-cell dysfunction and promoting glucose-stimulated insulin secretion (GSIS). Vincamine can improve glucose homeostasis in vivo and has potential in the study of type 2 diabetes (T2DM).