Valiglurax (VU0652957) is a potent, orally active and selective mGlu4 positive allosteric modulator with EC50 values of 64.6 nM and 197 nM for hmGlu4/Gqi5 and rmGlu4 GIRK, respectively. Valiglurax is a central nervous system (CNS) penetrant. Valiglurax can be used in research of Parkinson's disease.
K+-selective ionophoric cyclodepsipeptide; potassium ionophore which uncouples oxidative phosphorylation, induces apoptosis in murine thymocytes, inhibits NGF-induced neuronal differentiation and antagonizes ET-induced vasoconstriction.
K+-selective ionophoric cyclodepsipeptide; potassium ionophore which uncouples oxidative phosphorylation, induces apoptosis in murine thymocytes, inhibits NGF-induced neuronal differentiation and antagonizes ET-induced vasoconstriction.
Valnemulin hydrochloride is a broad-spectrum bacteriostatic agent inhibiting protein synthesis in bacteria by binding to the peptidyl transferase component of the 50S subunit of ribosomes.
Valproic acid (VPA) is an HDAC inhibitor with IC50 in the range of 0.5~2 mM. Valproic acid activates Notch1 signaling and inhibits proliferation in small cell lung cancer (SCLC) cells.
Valproic acid (VPA) is an HDAC inhibitor with IC50 in the range of 0.5~2 mM. Valproic acid activates Notch1 signaling and inhibits proliferation in small cell lung cancer (SCLC) cells.
Valproic acid (VPA) sodium is a histone deacetylase inhibitor which is reported to enhance central GABAergic neurotransmission and inhibit Na+ channels.
Valproic acid (VPA) sodium is a histone deacetylase inhibitor which is reported to enhance central GABAergic neurotransmission and inhibit Na+ channels.
Valproic acid (VPA) sodium is a histone deacetylase inhibitor which is reported to enhance central GABAergic neurotransmission and inhibit Na+ channels.
Valpromide (VPD) is a derivative of valproic acid (VPA) and is used as an antiepileptic drug.
Valpromide (VPD) is a derivative of valproic acid (VPA) and is used as an antiepileptic drug.