Tucatinib, also known as Irbinitinib and ONT-380, is an orally bioavailable inhibitor of the human epidermal growth factor receptor tyrosine kinase ErbB-2 (HER2).
Tucatinib, also known as Irbinitinib and ONT-380, is an orally bioavailable inhibitor of the human epidermal growth factor receptor tyrosine kinase ErbB-2 (HER2).
Tucatinib (Irbinitinib) hemiethanolate is a potent, orally active and selective HER2 inhibitor with an IC50 of 8 nM.
Tucatinib (Irbinitinib) hemiethanolate is a potent, orally active and selective HER2 inhibitor with an IC50 of 8 nM.
Tucidinostat (Chidamide) is a low nanomolar inhibitor of HDAC1, 2, 3, and 10, the HDAC isotypes well documented to be associated with the malignant phenotype with IC50 values of 95, 160, 67, 78 nM for HDAC1, 2, 3, 10 respectively.
Tucidinostat (Chidamide) is a low nanomolar inhibitor of HDAC1, 2, 3, and 10, the HDAC isotypes well documented to be associated with the malignant phenotype with IC50 values of 95, 160, 67, 78 nM for HDAC1, 2, 3, 10 respectively.
Tucidinostat (Chidamide) is a low nanomolar inhibitor of HDAC1, 2, 3, and 10, the HDAC isotypes well documented to be associated with the malignant phenotype with IC50 values of 95, 160, 67, 78 nM for HDAC1, 2, 3, 10 respectively.
Tucidinostat (Chidamide) is a low nanomolar inhibitor of HDAC1, 2, 3, and 10, the HDAC isotypes well documented to be associated with the malignant phenotype with IC50 values of 95, 160, 67, 78 nM for HDAC1, 2, 3, 10 respectively.
Tucidinostat (HBI-8000; Chidamide; CS-055) HCl is a benzamide type inhibitor of histone deacetylase (HDAC) isoenzymes 1, 2, 3 and 10 with IC50 values of 95, 160, 67, 78 nM for HDAC1, 2, 3, 10 respectively.
Tucidinostat (HBI-8000; Chidamide; CS-055) HCl is a benzamide type inhibitor of histone deacetylase (HDAC) isoenzymes 1, 2, 3 and 10 with IC50 values of 95, 160, 67, 78 nM for HDAC1, 2, 3, 10 respectively.
Tucidinostat (HBI-8000; Chidamide; CS-055) HCl is a benzamide type inhibitor of histone deacetylase (HDAC) isoenzymes 1, 2, 3 and 10 with IC50 values of 95, 160, 67, 78 nM for HDAC1, 2, 3, 10 respectively.
Tug-1375 is a free fatty acid receptor 2 (FFA2/GPR43) agonist with a pKi value of 6.69. TUG-1375 had no effect on FFA3, FFA4, PPARα, PPARγ, PPARδ, LXRα or LXRβ.