AF40431 is the first reported small molecule ligand of sortilin with IC50 of 4.4 µM and Kd of 0.7 µM. AF40431 binds to the neurotensin binding site of sortilin.
AF40431 is the first reported small molecule ligand of sortilin with IC50 of 4.4 µM and Kd of 0.7 µM. AF40431 binds to the neurotensin binding site of sortilin.
AF40431 is the first reported small molecule ligand of sortilin with IC50 of 4.4 µM and Kd of 0.7 µM. AF40431 binds to the neurotensin binding site of sortilin.
Afatinib (BIBW 2992) is a novel irreversible dual EGFR and HER2 tyrosine kinase inhibitor.
Afatinib (BIBW 2992) is a novel irreversible dual EGFR and HER2 tyrosine kinase inhibitor.
Afatinib (BIBW 2992) is a novel irreversible dual EGFR and HER2 tyrosine kinase inhibitor.