Hemoglobin Subunit Zeta (HBZ) is a member of the Globin family. The zeta chain is an alpha-type chain of mammalian embryonic Hemoglobin that is synthesized primarily in the yolk sac of the early embryo, while alpha-globin is produced throughout fetal growth and adult life. Recombinant Human Hemoglobin Subunit Zeta is produced by our E.coli expression...
Recombinant Human MMP-2 (also known as matrix metalloproteinase-2) is an enzyme that in humans is encoded by the MMP2 gene.It belongs to the matrix metalloproteinase (MMP) family. MMP-2 can act on several nonmatrix proteins such as big endothelial 1 and beta-type CGRP promoting vasoconstriction. The proenzyme needs to be activated by APMA for an activated...
Neutrophil activating peptide 2 (NAP2) is a carboxy-terminal fragment of platelet basic protein (PBP) found in human platelet α particles. Nap2 is a member of the CXC chemokine. Protein structure: CXCL7 (ALA59-ASP128), Accession # P02775.
CD40 Ligand (CD40L/CD154/TRAP) is a type II transmembrane glycoprotein that belongs to the TNF superfamily. The CD40 ligand stimulates B-cell proliferation and secretion of all immunoglobulin isotypes in the presence of cytokines. Recombinant Human CD40 Ligand is produced by E.coli expression system and the target gene encoding Met113-Leu261 is expressed.
Corticotropin-Releasing Factor-Binding Protein (CRHBP) is a 37 kDa secreted glycoprotein that binds both CRH and urocortin in a 42 kDa extracellular complex. CRHBP may inactivate CRH and may prevent inappropriate pituitary-adrenal stimulation in pregnancy.
Recombinant rat tumor necrosis factor produced in Pichia pastoris. TNF-alpha plays a major role in growth regulation, differentiation, inflammation, viral replication, tumorigenesis, and autoimmune disease. ED50 < 50.0 pg/ml
Pepinemab (VX 15/2503) is a human monoclonal antibody against SEMA4D, a signalling protein 4D (SEMA4D), also known as CD100, which is a regulator of neuronal development and plays a role in a variety of cellular processes. Pepinemab can be used in the study of various neurodegenerative diseases such as Alzheimer's disease by blocking the activity of SEMA4D.
Transforming growth factor beta 2 (TGF-β2) is a member of TGF-beta superfamily that shares a characteristic cysteine knot structure.
Recombinant Rat Insulin-like Growth Factor-1(E. coli) belonged to the insulin gene family, it is mitogenic polypeptide growth factor that stimulates the proliferation and survival of various cell types including muscle, bone, and cartilage tissue in vitro.
Recombinant Human IL-6 is an interleukin that in humans is encoded by the IL-6 gene and acts as both a pro-inflammatory and anti-inflammatory cytokine.
Cytotoxic Tlymphocyte 4(CTLA-4,CD152), is a type I transmembrane T cell inhibitory molecule that is a member of the Ig superfamily. CTLA4 transmits an inhibitory signal to T cells, whereas CD28 transmits a stimulatory signal.
Rademikibart is a human IgG4ҡ monoclonal antibody that targets IL-4 Rα to block inflammatory signaling induced by IL-4 and IL-13, two important cytokines that drive allergic inflammation, and binds to the human IL-4Rα epitope with a KD of 20.7 pM. Rademikibart does not bind to IL-4Rα from other species. Rademikibart does not bind to IL-4Rα of other...