RIPK3 is a kinase that controls necroptosis and apoptosis. In necroptosis, activated by TNF-α and ZBP1, RIPK3 phosphorylates MLKL, leading to membrane damage. Necroptosis is dependent on receptor-interacting protein kinase 3 (RIPK3), a protein shown to play an important role in experimental models of critical illness. RIPK3 promotes kidney tubular injury...
C1QTNF1 is a secreted protein,contains 1 C1q domain and 1 collagen-like domain. C1QTNF1 is a novel adipokine, providing a significant framework to further address the physiological functions and mechanisms of the action of this family of secreted glycoproteins in normal and disease states. C1QTNF1 increases the production of aldosterone.
Mouse beta -NGF is a homodimer of two 120 amino acid polypeptides. β-NGF acts as a growth and differentiation factor for B lymphocytes, and enhances B-cell survival.
Recombinant Human Interleukin-31 (IL-31) signals through IL-31 receptor A and oncostatin M receptor subunits and can activate STAT3 through receptors and maybe involve in skin immunity.
Recombinant human fibroblast growth factor 7/ keratinocyte growth factor 7 is produced by the escherichia coli expression system and expresses the target gene encoding CYS32-THR194.
Tremelimumab (Ticilimumab) is a fully humanized monoclonal antibody specific for cytotoxic T-lymphocyte antigen-4 (CTLA-4) and can be used for metastatic melanoma research.
Recombinant Human Granulocyte-Macrophage Colony Stimulating Factor is a hematopoietic growth factor and immune modulator.
Fibroblast Growth Factor-basic (FGF-basic), also known as FGF-2, is a pleiotropic cytokine and one of the prototypic members of the heparin-binding FGF family. FGF-basic regulates a variety of processes including cell proliferation, differentiation, survival, adhesion, motility, apoptosis, limb formation and wound healing. FGF-basic is a non-glycosylated...
Interleukin-5 (IL-5) is responsible for the activities attributed to eosinophil differentiating factor, B cell growth factor II and T cell-replacing factor (TRF). IL-5 plays an important role in inducing cell-mediated immunity against parasitic infections and certain tumors.
IL-27 is a heterodimeric cytokine which belongs to the IL-6/IL-12 family of long type I cytokines. Recombinant Mouse Interleukin-27 Subunit Alpha and Interleukin-27 Subunit Beta expressed the target gene encoding Tyr19-Pro228&Phe29-Ser234 with a 6His tag at the C-terminus.
Serplulimab (HLX 10) is humanized monoclonal anti-PD-1 antibody. Serplulimab can be used in research of small cell lung cancer.
IFN-γ is the major interferon produced by mitogenically or antigenically stimulated lymphocytes. Human Interferon gamma (hIFN-γ) is amacrophage‐activating factor. IFN-γ is also implicated in resistance to NK cell and CTL responses and in immune escape in a variety of cancers.