Chemical
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- Catálogos PDF
Chemical Hay 28543 productos.
SC79
SC79 is a specific and BBB permeable Akt activator used to enhance Akt activity. SC79 activates Akt in the cytosol and inhibits Akt membrane translocation. SC79 specifically binds to the PH domain of Akt. *The compound is unstable in solutions, freshly prepared is recommended
Risdiplam
Risdiplam (also known as RG7916 and RO7034067) is a gene splicing modulator (neuromuscular disease) that distributes into the central nervous system (CNS) and peripheral tissues.
LMTK3-IN-1
LMTK3-IN-1 is an ATP-competitive inhibitor of lemur tyrosine kinase 3 (LMTK3) (Kd=2.5 μM), that acts by degrading LMTK3 via the ubiquitin-proteasome pathway.
Paritaprevir
Paritaprevir (ABT-450) is a potent non-structural protein 3/4A (NS3/4A) protease inhibitor with EC50 values of 1 and 0.21 nM for HCV 1a and 1b, respectively.
SANT-1
SANT-1 directly binds to Smoothened (Smo) receptor with Kd of 1.2 nM and inhibits Smo agonist effects with IC50 of 20 nM.
Trichostatin A
Trichostatin A (TSA) is a potent and specific inhibitor of mammalian histone deacetylase (HDAC) class I/II, with an IC50 value of 1.8 nM for HDAC.
NFAT Inhibitor-1 (VIVIT peptide)
NFAT Inhibitor-1 (VIVIT peptide) is a cell-permeable peptide inhibitor of nuclear factor of activated Tcells (NFAT), it is superior at inhibiting calcineurin-mediated dephosphorylation of NFAT1, NFAT2, and NFAT4 in cell extracts.
Nidufexor
Nidufexor (LMB763) is an orally available farnesoid X receptor (FXR) agonist.
Canagliflozin
Canagliflozin is a potent, selective sodium glucose co-transporter 2 inhibitor.
CCR8 Antagonist 1
CCR8 Antagonist 1 is a potent human CCR8 antagonist with a Ki value of 1.6 nM.
N-Acetylneuraminic acid
N-Acetylneuraminic acid is a nine-carbon, sialic acid monosaccharide commonly found in glycoproteins on cell membranes and in glycolipids such as gangliosides in mammalian cells. Studies suggest that N-Acetylneuraminic acid is useful biologically in neurotransmission, leukocyte extravasation, viral or bacterial infections and carbohydrate-protein...
Fumonisin B1
Fumonisin B1 is a mycotoxin produced from Fusarium moniliforme. Fumonisin B1 is a potent inhibitor of sphingosine N-acyltransferase (ceramide synthase) and disrupts de novo sphingolipid biosynthesis. Fumonisin B1 is the most abundant and toxic fumonisin.