Chemical
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- Catálogos PDF
Chemical Hay 28543 productos.
H3B-8800
H3B-8800 is an orally available small molecule modulator of splicing factor 3B subunit 1 (SF3B1). H3B-8800 binds SF3B1 and exhibits significant antitumor activity by eliminating disruption of mRNA splicing.
GSK046
GSK046 (iBET-BD2) is an effective, selective and orally active inhibitor of the BD2 bromine domain of the BET protein,IC50 The values are 264 nM (BRD2 BD2), 98 nM (BRD3 BD2), 49 nM (BRD4 BD2), and 214 nM (BRDT BD2). GSK046 has immunomodulatory activity.
GSK046
GSK046 (iBET-BD2) is an effective, selective and orally active inhibitor of the BD2 bromine domain of the BET protein,IC50 The values are 264 nM (BRD2 BD2), 98 nM (BRD3 BD2), 49 nM (BRD4 BD2), and 214 nM (BRDT BD2). GSK046 has immunomodulatory activity.
GSK046
GSK046 (iBET-BD2) is an effective, selective and orally active inhibitor of the BD2 bromine domain of the BET protein,IC50 The values are 264 nM (BRD2 BD2), 98 nM (BRD3 BD2), 49 nM (BRD4 BD2), and 214 nM (BRDT BD2). GSK046 has immunomodulatory activity.
GSK046
GSK046 (iBET-BD2) is an effective, selective and orally active inhibitor of the BD2 bromine domain of the BET protein,IC50 The values are 264 nM (BRD2 BD2), 98 nM (BRD3 BD2), 49 nM (BRD4 BD2), and 214 nM (BRDT BD2). GSK046 has immunomodulatory activity.
S-Methylisothiourea sulfate
S-Methylisothiourea sulfate is a highly effective, selective, competitive inducible nitric oxide synthase (iNOS) inhibitor. S-Methylisothiourea sulfate plays a beneficial role in rodent models of septic shock.
Dextran (Mw 70000)
Dextran (Mw 70000) has an inhibitory effect on platelet aggregation and coagulation factors, and can replace part of the whole blood during blood transfusion, and is often used as a plasma volume expander (plasma replacement).
Succinyl phosphonate trisodium salt
Succinyl phosphonate trisodium salt is an inhibitor of α -ketoglutarate dehydrogenase (KGDHC) that effectively inhibits KGDHC in muscle, bacteria, brain, and human fibroblasts. Succinyl phosphonate trisodium salt inhibits 2-oxyglutarate dehydrogenase (OGDH) and damages cancer cell viability in a cell-specific, metabolically dependent manner.
Succinyl phosphonate trisodium salt
Succinyl phosphonate trisodium salt is an inhibitor of α -ketoglutarate dehydrogenase (KGDHC) that effectively inhibits KGDHC in muscle, bacteria, brain, and human fibroblasts. Succinyl phosphonate trisodium salt inhibits 2-oxyglutarate dehydrogenase (OGDH) and damages cancer cell viability in a cell-specific, metabolically dependent manner.
Eclitasertib
Eclitasertib (DNL-758) is a receptor interaction protein kinase 1 (RIPK1) inhibitor, with IC50 value of
Eclitasertib
Eclitasertib (DNL-758) is a receptor interaction protein kinase 1 (RIPK1) inhibitor, with IC50 value of
Zandelisib
Zandelisib (ME-401) is a PI3K inhibitor that selectively inhibits P110 δ with an IC50 value of 3.5 nM. Zandelisib has antitumor effects.