Etelcalcetide Hydrochloride (AMG 416 Hydrochloride) is a synthetic peptide that acts as a calcium-sensitive receptor (CaSR) activator. Etelcalcetide hydrochloride effectively reduces parathyroid hormone (PTH) concentration in patients with secondary hyperparathyroidism undergoing hemodialysis.
Etelcalcetide Hydrochloride (AMG 416 Hydrochloride) is a synthetic peptide that acts as a calcium-sensitive receptor (CaSR) activator. Etelcalcetide hydrochloride effectively reduces parathyroid hormone (PTH) concentration in patients with secondary hyperparathyroidism undergoing hemodialysis.
Etelcalcetide Hydrochloride (AMG 416 Hydrochloride) is a synthetic peptide that acts as a calcium-sensitive receptor (CaSR) activator. Etelcalcetide hydrochloride effectively reduces parathyroid hormone (PTH) concentration in patients with secondary hyperparathyroidism undergoing hemodialysis.
A939572 is a potent, orally active stearyl CoA desaturase 1 SCD1 inhibitor that acts on mSCD1 and hSCD1 with IC50
Tch-165 is a small molecule modulator of proteasome assembly that increases 20S levels and promotes 20S-mediated protein degradation.
2' -deoxy-5-formylcytidine is an effective internal triplet photosensitizer in DNA. 2' -deoxy-5-formylcytidine can be used as a new hot spot for DNA photodamage.
Rhodamine 6G (Rhodamine 6G) is a fluorescent tracer that can bind to mitochondria, with a maximum excitation/emission wavelength of 525nm/550nm. It emits orange-red fluorescence and should be stored away from light.
GeA-69 is a cell-penetrating selective allosteric inhibitor targeting Macrodomain 2 (MD2) with a Kd of 2.1 µM.
GeA-69 is a cell-penetrating selective allosteric inhibitor targeting Macrodomain 2 (MD2) with a Kd of 2.1 µM.
C25-140, a first-in-class, orally active, and fairly selective TRAF6-Ubc13 inhibitor, directly binds to TRAF6, and blocks the interaction of TRAF6 with Ubc13. C25-140 lowers TRAF6 activity, reduces NF-κB activation, and combats autoimmunity.
C25-140, a first-in-class, orally active, and fairly selective TRAF6-Ubc13 inhibitor, directly binds to TRAF6, and blocks the interaction of TRAF6 with Ubc13. C25-140 lowers TRAF6 activity, reduces NF-κB activation, and combats autoimmunity.
G-5555 is a potent p21-activated kinase 1 (PAK1) inhibitor with Kis of 3.7 nM and 11 nM for PAK1 and PAK2, respectively.